Evidence map›Paper›PMID 30887755›Full record

ArticleJournal of gynecologic oncology2019

Prospective study of the efficacy and utility of TP53 mutations in circulating tumor DNA as a non-invasive biomarker of treatment response monitoring in patients with high-grade serous ovarian carcinoma.

Yong Man Kim, Shin Wha Lee, Young Jae Lee, Ha Young Lee, Jong Eun Lee, Eun Kyung Choi

Open access · diamondAbstract read
In one paragraph

Article in Journal of gynecologic oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 74 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Frontiers in oncology · 2025
    Article
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yong Man KimDepartment of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3225-5748
Shin Wha LeeDepartment of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. swhlee@amc.seoul.kr.ORCID https://orcid.org/0000-0002-5088-1905
Young Jae LeeDepartment of Obstetrics and Gynecology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6557-2454
Ha Young LeeAsan Institute for Life Sciences, Seoul, Korea.ORCID https://orcid.org/0000-0002-5128-4221
Jong Eun LeeDNA Link, Inc., Seoul, Korea.ORCID https://orcid.org/0000-0001-8115-3743
Eun Kyung ChoiInstitute for Innovative Cancer Research, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8465-1529
Ulsan College · KRAsan Medical Center · KRDNA Link (South Korea) · KR

Funding

Asan Institute for Life Sciences, Asan Medical Center 2015-588Asan Institute for Life Sciences, Asan Medical Center 2016-731
6 · The paper itself

Abstract

objectiveSomatic

methods

resultsDirect sequencing analysis of 103 tumor tissues from 61 HGSOC patients confirmed

conclusion

Indexed as

DNA Mutational AnalysisBiomarkers, TumorCA-125 AntigenChemotherapy, AdjuvantCirculating Tumor DNACombined Modality TherapyCystadenocarcinoma, SerousFemaleHumansMiddle AgedMonitoring, PhysiologicOvarian NeoplasmsOvariectomyPredictive Value of TestsPrognosisProspective StudiesBiomarkers, TumorCA-125 AntigenCirculating Tumor DNATP53 protein, humanTumor Suppressor Protein p53DNA Mutational AnalysisOvarian CancerTumor BiomarkersTumor Suppressor Protein p53

Identifiers

PMID30887755
PMCPMC6424844
OpenAlexW2903003331

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.