Evidence map›Paper›PMID 30887749›Full record

ArticleKorean journal of radiology2019

Distinguishing between Thymic Epithelial Tumors and Benign Cysts via Computed Tomography.

Sang Hyup Lee, Soon Ho Yoon, Ju Gang Nam, Hyung Jin Kim, Su Yeon Ahn, Hee Kyung Kim, Hyun Ju Lee, Hwan Hee Lee, Gi Jeong Cheon, Jin Mo Goo

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. How can the rate of nontherapeutic thymectomy be reduced?Interactive cardiovascular and thoracic surgery · 2022
    Article
  8. Review
  9. CT and MRI findings of cystic renal cell carcinoma: comparison with cystic collecting duct carcinoma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2021
    Article
  10. Review
  11. Article
  12. Clinical Experience with Thymic Cystectomy: A Single-Institution Study of 117 Cases from 2013 to 2019.Medical science monitor : international medical journal of experimental and clinical research · 2020
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sang Hyup LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6773-2965
Soon Ho YoonDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3700-0165
Ju Gang NamDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3991-4523
Hyung Jin KimDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0722-0033
Su Yeon AhnDepartment of Radiology, Konkuk University School of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-3370-0498
Hee Kyung KimDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7400-1311
Hyun Ju LeeDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-5748-2096
Hwan Hee LeeDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.
Gi Jeong CheonDepartment of Nuclear Medicine, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-1360-5186
Jin Mo GooDepartment of Radiology, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1791-7942
Seoul National University · KRKonkuk University · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate whether computed tomography (CT) and fluorine-18-labeled fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET) may be applied to distinguish thymic epithelial tumors (TETs) from benign cysts in the anterior mediastinum. MATERIALS AND

methodsWe included 262 consecutive patients with pathologically proven TETs and benign cysts 5 cm or smaller who underwent preoperative CT scans. In addition to conventional morphological and ancillary CT findings, the relationship between the lesion and the adjacent mediastinal pleura was evaluated qualitatively and quantitatively. Mean lesion attenuation was measured on CT images. The maximum standardized uptake value (SUVmax) was obtained with FDG-PET scans in 40 patients. CT predictors for TETs were identified with multivariate logistic regression analysis. For validation, we assessed the diagnostic accuracy and inter-observer agreement between four radiologists in a size-matched set of 24 cysts and 24 TETs using a receiver operating characteristic curve before and after being informed of the study findings.

resultsThe multivariate analysis showed that post-contrast attenuation of 60 Hounsfield unit or higher (odds ratio [OR], 12.734; 95% confidence interval [CI], 2.506-64.705;

conclusionPost-contrast CT attenuation, protrusion from the mediastinal pleura, and SUVmax were useful imaging features for distinguishing TETs from cysts in the anterior mediastinum.

Indexed as

Tomography, X-Ray ComputedAdultAgedAged, 80 and overArea Under CurveCystsFemaleFluorodeoxyglucose F18HumansMaleMediastinumMiddle AgedMultivariate AnalysisNeoplasms, Glandular and EpithelialPositron-Emission TomographyRetrospective StudiesFluorodeoxyglucose F18Computed tomographyCystic massFDG-PET/CTMediastinumThymic tumor

Identifiers

PMID30887749
PMCPMC6424822
OpenAlexW2921323485

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.