Evidence map›Paper›PMID 30887637›Full record

Trial reportMicrocirculation (New York, N.Y. : 1994)2019

Prediction of renal allograft chronic rejection using a model based on contrast-enhanced ultrasonography.

Cheng Yang, Shengdi Wu, Ping Yang, Guoguo Shang, Ruochen Qi, Ming Xu, Ruiming Rong, Tongyu Zhu, Wanyuan He

Abstract readClinical Trial
In one paragraph

Trial report in Microcirculation (New York, N.Y. : 1994), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Cheng YangDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.ORCID 0000-0003-4060-2746
Shengdi WuDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ping YangDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai Institute of Imaging Medicine, Shanghai, China.
Guoguo ShangDepartment of Pathology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ruochen QiDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ming XuDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Ruiming RongDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Tongyu ZhuDepartment of Urology, Zhongshan Hospital, Fudan University, Shanghai, China.
Wanyuan HeDepartment of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai Institute of Imaging Medicine, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the application of contrast-enhanced ultrasonography (CEUS) for the diagnosis of renal allograft chronic rejection (CR).

methodsA total of 104 patients who were suspected to have AR or CR were enrolled in this study (derivation group, n = 66; validation group, n = 38). Before biopsy, all patients received an ultrasound examination.

resultsIn the CR group, rising time (RT) and time to peak (TTP) of medulla (RTm and TTPm, respectively) were significantly longer compared to those in the AR group. The kidney volume was significantly decreased in the CR group but was increased in the AR group. In the derivation group, age, change in kidney volume, and TTPm were identified as independent predictors by multivariate analysis. Based on the multivariate analysis results and area under receiver operating characteristic (ROC) curves (AUROCs) of individual markers, we constructed a new index as follows: P = -5.424 + 0.074 × age -9.818 × kidney volume change + 0.115 × TTPm; New Index = e

conclusionIn conclusion, the new index provides a new diagnosis model for CR.

Indexed as

Graft RejectionKidneyKidney TransplantationAdultAllograftsChronic DiseaseContrast MediaFemaleHumansMaleMiddle AgedUltrasonographyContrast Mediacontrast mediadiagnostic testgraft Rejectionrenal transplantationultrasonography

Identifiers

PMID30887637
PMCPMC6767498

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.