ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2019
Health-related quality of life in injury patients: the added value of extending the EQ-5D-3L with a cognitive dimension.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychometric properties of the health-related quality of life instrument with 8 items: a systematic review and meta-analysis.Health and quality of life outcomes · 2026Pooled it
- Psychometric validation of a cognition and social participation bolt-on for the EQ-5D-5L in SARS-CoV-2 infected German healthcare workers.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Developing and testing bolt-on enhanced EQ-5D-5L for assessing Chinese patients with chronic obstructive pulmonary disease: a mixed-methods study protocol.BMJ open respiratory research · 2026Article
- Validity of EQ-5D-5L breathing and cognition bolt-ons in non-hospitalized patients after COVID-19.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- The added value of the cognition, dining, gastrointestinal problems, sleep and tiredness bolt-on dimensions to the EQ-5D-5L in patients with coeliac disease.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Testing four cognition bolt-on items to the EQ-5D in a general Chinese population.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Quality of life after stereotactic radiosurgery for brain metastasis: an assessment from a prospective national registry.Journal of neuro-oncology · 2025Article
- Exploring potential EQ-5D bolt-on dimensions with a qualitative approach: an interview study in Hong Kong SAR, China.Health and quality of life outcomes · 2024Article
- Enhancing EQ-5D-5L Sensitivity in Capturing the Most Common Symptoms in Post-COVID-19 Patients: An Exploratory Cross-Sectional Study with a Focus on Fatigue, Memory/Concentration Problems and Dyspnea Dimensions.International journal of environmental research and public health · 2024Article
- One-year outcomes of traumatic injuries among survivors in Ethiopia: a cross-sectional study on the employment outcomes and functioning state.Trauma surgery & acute care open · 2024Article
- Sensitivity of the EQ-5D-5L for fatigue and cognitive problems and their added value in Q-fever patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Assessing Health-Related Quality of Life of Adult Patients with Intermediate Burns: The Added Value of an Itching and Cognition Item for the EQ-5D: A Retrospective Observational Study.European burn journal · 2022Article
- Adding a fatigue item to the EQ-5D-5L improves its psychometric performance in the general population.Journal of patient-reported outcomes · 2022Article
- Factors Affecting Health-Related Quality of Life in Multimorbidity.Healthcare (Basel, Switzerland) · 2021Article
- Prognostic factors for recovery of health status after injury: a prospective multicentre cohort study.BMJ open · 2021Article
- Does the EQ-5D-5L benefit from extension with a cognitive domain: Testing a multi-criteria psychometric strategy in trauma patients.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
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6 authors.
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Abstract
introductionThe EQ-5D is frequently used to understand the development of health-related quality of life (HRQL) following injury. However, the lack of a cognition dimension is generally felt as disadvantageous as many injuries involve cognitive effects. We aimed to assess the added value of a cognitive dimension in a cohort of injury patients.
methodsWe analyzed EQ-5D-3L extended with cognition (EQ-5D + C) dimension responses of 5346 adult injury patients. We studied dimension dependency, assessed the additional effect of the cognitive dimension on the EQ-VAS, and, using the EQ-VAS as a dependent variable, determined the impact of EQ-5D and EQ-5D + C attributes in multivariate regression analyses.
resultsExtreme cognitive problems combined with no problems on other dimensions are uncommon, whereas severe problems on other dimensions frequently occur without cognitive problems. The EQ-VAS significantly decreased when cognitive problems emerged. Univariate regression analyses indicated that all EQ-5D + C dimensions were significantly associated with the EQ-VAS. Exploratory analyses showed that using any set of five of the six EQ-5D + C dimensions resulted in almost identical explained variance, and adding the remaining 6th dimension resulted in a similar additional impact.
conclusionsThe addition of the cognition dimension increased the explanatory power of the EQ-5D-3L. Although the increase in explanatory power was relatively small after the cognition dimension was added, the decrease of HRQoL (measured with the EQ-VAS) resulting from cognitive problems was comparable to the decreases resulting from other EQ-5D dimensions.
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