ArticleJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019
Short- and Long-Term Outcomes After Live-Donor Transplantation with Hyper-Reduced Liver Grafts in Low-Weight Pediatric Recipients.
Article in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Left Lateral Segment Liver Transplantation in Small Infants: Outcomes From a High-Volume Center.Pediatric transplantation · 2026Article
- Hyper-reduced grafts in living donor liver transplant: Techniques and outcomes.World journal of transplantation · 2025Article
- Large-for-size syndrome prophylaxis in infant liver recipients with low body mass.World journal of transplantation · 2025Review
- Understanding Local Hemodynamic Changes After Liver Transplant: Different Entities or Simply Different Sides to the Same Coin?Transplantation direct · 2022Review
- Review
- Alternatives to left lateral sector in paediatric liver transplantation-a systematic review on monosegmental and reduced grafts.Hepatobiliary surgery and nutrition · 2022Review
- Pediatric living donor liver transplantation (LDLT): Short- and long-term outcomes during sixteen years period at a single centre- A retrospective cohort study.Annals of medicine and surgery (2012) · 2022Article
- Pediatric deceased donor liver transplantation withAnnals of hepato-biliary-pancreatic surgery · 2021Article
- Dextroplantation of a reduced left lateral section graft in an infant undergoing living donor liver transplantation.Annals of hepato-biliary-pancreatic surgery · 2021Article
- Pediatric liver transplantation with hyperreduced left lateral segment graft.Annals of hepato-biliary-pancreatic surgery · 2020Article
- Pediatric split liver transplantation using a hyperreduced left lateral segment graft in an infant weighing 4 kg.Korean journal of transplantation · 2020Article
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Authors and funding
12 authors.
Funding
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Abstract
objectiveTo evaluate short- and long-term outcomes after live-donor liver transplantation (LT) with hyper-reduced grafts in low-weight pediatric recipients. LT is an established curative therapy for children with end-stage chronic liver disease or acute liver failure. A major problem in pediatric LT has been the lack of size-matched donor organs. The disadvantage of the use of large-for-size grafts is the insufficient tissue oxygenation and graft compression, which result in poor outcomes. The shortage of suitable donors is most notable in children under 10 kg. To overcome such obstacle, in situ hyper-reduced live-donor liver grafts have been introduced. Available articles in the literature are based on small samples and are deficient in long-term follow-up.
methodsA single-cohort, retrospective analysis was conducted including 59 pediatric patients under 10 kg who underwent hyper-reduced (in situ "a la carte" left lateral segment reduction) live-donor LT (LDLT) between February 1994 and February 2018.
resultsThe most frequent cause of liver failure was biliary atresia (70%). Median recipient weight was 8 kg. Vascular complications were confirmed in 15% of the sample, while 45% presented biliary complications. Median follow-up time was 40.3 months. Ten-year overall survival rate was 74%. Pediatric end-stage liver disease score > 23 was associated with a higher risk of post-operative complications.
conclusionLDLT can be undertaken in children with body weight < 10 kg achieving good results in high-volume centers by experienced surgeons.
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