Evidence map›Paper›PMID 30887257›Full record

ReviewCurrent gastroenterology reports2019

Obesity, Motility, Diet, and Intestinal Microbiota-Connecting the Dots.

Maya Fayfman, Kristen Flint, Shanthi Srinivasan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. The Influence of Obesity on Small Bowel Capsule Endoscopy.Gastroenterology research and practice · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Role of microbial dysbiosis in carcinogenesis & cancer therapies.The Indian journal of medical research · 2020
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maya FayfmanEmory University School of Medicine, Atlanta, GA, USA.
Kristen FlintEmory University School of Medicine, Atlanta, GA, USA.
Shanthi SrinivasanEmory University School of Medicine, Atlanta, GA, USA. ssrini2@emory.edu.
Emory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe goal of the present review is to explore the relationship between dietary changes and alterations in gut microbiota that contribute to disorders of gut motility and obesity. RECENT

findingsWe review the microbiota changes that are seen in obesity, diarrhea, and constipation and look at potential mechanisms of how dysbiosis can predispose to these. We find that microbial metabolites, particularly short chain fatty acids, can lead to signaling changes in the host enterocytes. Microbial alteration leading to both motility disorders and obesity may be mediated by the release of hormones including glucagon-like peptides 1 and 2 (GLP-1, GLP-2) and polypeptide YY (PYY). These pathways provide avenues for microbiota-targeted interventions that can treat both disorders of motility and obesity. In summary, multiple mechanisms contribute to the interplay between the microbial dysbiosis, obesity, and dysmotility.

Indexed as

DietGastrointestinal MicrobiomeConstipationDiarrheaDysbiosisGastrointestinal MotilityHumansObesityConstipationDiarrheaDysmotilityGut microbiomeObesity

Identifiers

PMID30887257
OpenAlexW2922042229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.