Evidence map›Paper›PMID 30887206›Full record

ArticleEuropean radiology2019

Can amide proton transfer-weighted imaging differentiate tumor grade and predict Ki-67 proliferation status of meningioma?

Hao Yu, Xinrui Wen, Pingping Wu, Yueqin Chen, Tianyu Zou, Xianlong Wang, Shanshan Jiang, Jinyuan Zhou, Zhibo Wen

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Hao YuDepartment of Radiology, Affiliated Hospital of Jining Medical University, Jining Medical University, Guhuai Road No. 89, Rencheng District, Jining, 272029, Shandong, China.
Xinrui WenDepartment of Neurology, Zhujiang Hospital, Southern Medical University, Gongye Road M No. 253, Haizhu District, Guangzhou, 510282, Guangdong, China.
Pingping WuDepartment of Clinical Laboratory, Jining NO. 1 People's Hospital, 6 Jiankang Road, Jining, 272011, China.
Yueqin ChenDepartment of Radiology, Affiliated Hospital of Jining Medical University, Jining Medical University, Guhuai Road No. 89, Rencheng District, Jining, 272029, Shandong, China.
Tianyu ZouDepartment of Radiology, Weihai Municipal Hospital, Heping Road M No.70, Weihai, 264200, Shandong, China.
Xianlong WangDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Gongye Road M No. 253, Haizhu District, Guangzhou, 510282, Guangdong, China.
Shanshan JiangDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Gongye Road M No. 253, Haizhu District, Guangzhou, 510282, Guangdong, China.
Jinyuan ZhouDivision of MR Research, Department of Radiology, Johns Hopkins University School of Medicine, 600N. Wolfe Street, Park 336, Baltimore, MD, 21287, USA.
Zhibo WenDepartment of Radiology, Zhujiang Hospital, Southern Medical University, Gongye Road M No. 253, Haizhu District, Guangzhou, 510282, Guangdong, China. zhibowen@163.com.
Southern Medical University · CNJohns Hopkins Medicine · USAffiliated Hospital of Jining Medical University · CNJining First People's Hospital · CNWeihai Municipal Hospital · CNZhujiang Hospital · CN

Funding

Amide Proton Transfer (APT) MRI of Brain Tumors at 3T and 7TR01EB009731 · NIBIB · JOHNS HOPKINS UNIVERSITY · PI ZHOU, JINYUAN · 2009 to 2016
$2.9M
Academic-Industrial Partnership to Develop Clinical Brain Cancer ImagingR01CA166171 · NCI · JOHNS HOPKINS UNIVERSITY · PI VAN ZIJL, PETER CM, ZHOU, JINYUAN · 2013 to 2017
$2.4M
Guangdong Provincial Natural Science Foundation 2014A030313271Guangdong Provincial Science and Technology Project 2014A020212726NCI NIH HHS R01 CA166171NIBIB NIH HHS R01 EB009731NIH HHS R01CA166171NIH HHS R01EB009731Southern Medical University clinical research project LC2016ZD028
6 · The paper itself

Abstract

objectivesTo determine the utility of the amide proton transfer-weighted MR imaging in differentiating the WHO grade and predict proliferative activity of meningioma.

methodsFifty-three patients with WHO grade I meningiomas and 26 patients with WHO grade II meningiomas underwent conventional and APT-weighted sequences on a 3.0 Tesla MR before clinical intervention. The APT-weighted (APTw) parameters in the solid tumor region were obtained and compared between two grades using the t test; the receiver operating characteristic (ROC) curve was used to assess the best parameter for predicting the grade of meningiomas. Pearson's correlation coefficient was calculated between the APTw

resultsThe APTw

conclusionAs a noninvasive imaging method, the ability of APTw-MR imaging in differentiating the grade of meningiomas is limited, but the technology can be used to predict the proliferative activity of meningioma. KEY POINTS: • The APTw

Indexed as

AmidesProtonsAdultAgedCell ProliferationFemaleHumansKi-67 AntigenMagnetic Resonance ImagingMaleMeningeal NeoplasmsMeningiomaMiddle AgedNeoplasm GradingROC CurveAmidesKi-67 AntigenProtonsAmide proton transferCell proliferationMagnetic resonance imagingMeningiomaTumor grading

Identifiers

PMID30887206
PMCPMC6717551
OpenAlexW2921644523

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.