ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2019
Assessment of the effect of ten heading time genes on reproductive transition and yield components in rice using a CRISPR/Cas9 system.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CCT domain-containing genes in cereal crops: flowering time and beyond.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Pooled it
- Accelerated breeding for early-maturing and aromatic glutinous restorer lines with CRISPR/Cas9-mediated targeted editing for hybrid rice.BMC plant biology · 2026Article
- Review
- Mapping and validation of QTkw.cau-3DL, a major QTL controlling thousand-kernel weight in wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Improving Rice Quality by Regulating the Heading Dates of Rice Varieties without Yield Penalties.Plants (Basel, Switzerland) · 2024Article
- Enhancing Yield and Improving Grain Quality in Japonica Rice: Targeted EHD1 Editing via CRISPR-Cas9 in Low-Latitude Adaptation.Current issues in molecular biology · 2024Article
- Fine-tuning rice heading date through multiplex editing of the regulatory regions of key genes by CRISPR-Cas9.Plant biotechnology journal · 2024Article
- Unlocking Nature's Clock: CRISPR Technology in Flowering Time Engineering.Plants (Basel, Switzerland) · 2023Review
- Genome-wide association analysis identifies natural allelic variants associated with panicle architecture variation in African rice, Oryza glaberrima Steud.G3 (Bethesda, Md.) · 2023Article
- Extra-large G proteins have extra-large effects on agronomic traits and stress tolerance in maize and rice.Trends in plant science · 2023Review
- Gene Editing for Plant Resistance to Abiotic Factors: A Systematic Review.Plants (Basel, Switzerland) · 2023Review
- Regain flood adaptation in rice through a 14-3-3 protein OsGF14h.Nature communications · 2022Article
- Reverse genetic approaches for breeding nutrient-rich and climate-resilient cereal and food legume crops.Heredity · 2022Article
- Genetic dissection of quantitative trait loci for grain size and weight by high-resolution genetic mapping in bread wheat (Triticum aestivum L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- The Generic Risks and the Potential of SDN-1 Applications in Crop Plants.Plants (Basel, Switzerland) · 2021Review
- Efficient Breeding of Early-Maturing Rice Cultivar by Editing PHYC via CRISPR/Cas9.Rice (New York, N.Y.) · 2021Article
- Fine-tuning Flowering Time via Genome Editing of Upstream Open Reading Frames of Heading Date 2 in Rice.Rice (New York, N.Y.) · 2021Article
- Hotter, drier, CRISPR: the latest edit on climate change.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Review
- Modification of cereal plant architecture by genome editing to improve yields.Plant cell reports · 2021Review
- Elucidation of the relationship between yield and heading date using CRISPR/Cas9 system-induced mutation in the flowering pathway across a large latitudinal gradient.Molecular breeding : new strategies in plant improvement · 2021Article
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4 authors.
Funding
Abstract
key messageWe demonstrated the effect of heading time genes on reproductive transition and yield components under an identical genetic background using CRISPR/Cas9 gene-editing technology, and we propose that the elite allele will provide a new breeding strategy for rice breeding in high-latitude regions. Heading date is a factor closely associated with grain yield in rice (Oryza sativa L). In recent decades, a number of genes responsible for heading time have been identified, the variation of which contributes to the expansion of the rice cultivation area. However, it is difficult to compare the phenotypic effects of these genes due to the different genetic backgrounds. In this study, we generated 14 heading time mutants using CRISPR/Cas9 gene-editing technology and marker-assisted selection with a japonica Sasanishiki wild-type (WT) genetic background. Photoperiod sensitivity, the relationship between days to heading (DTH), and yield components of mutants were investigated. We found that the yield increases with increases in DTH, but eventually plateaus at maximum and then began to decrease, whereas the biomass continued to increase. The mutants exerted distinctly different effects on DTH and yield components. The convergent double mutants had severe yield reduction compared with single mutants, even with a DTH that was similar to that of single mutants. We also found that an elite mutant of se14 achieved a yield equal to that of the WT, but with heading occurring 10 days earlier. A sequence analysis of 72 cultivars collected from the japonica cultivated zone shows that elite se14 mutants have not been applied to rice breeding. Our study demonstrates the effect of heading time genes on reproductive transition and yield components under an identical genetic background. These results may provide new insights into rice breeding using heading time mutants.
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