Evidence map›Paper›PMID 30887077›Full record

ArticleExperimental brain research2019

c-Fos expression in the limbic thalamus following thermoregulatory and wake-sleep changes in the rat.

Marco Luppi, Matteo Cerri, Alessia Di Cristoforo, Timna Hitrec, Daniela Dentico, Flavia Del Vecchio, Davide Martelli, Emanuele Perez, Domenico Tupone, Giovanni Zamboni and 1 more

Abstract read
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In one paragraph

Article in Experimental brain research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 4 countries.

Marco LuppiDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy. marco.luppi@unibo.it.ORCID http://orcid.org/0000-0002-9462-5014
Matteo CerriDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0003-3556-305X
Alessia Di CristoforoDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0003-4444-0019
Timna HitrecDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0002-9296-3482
Daniela DenticoUniversity of Wisconsin-Madison, 625 W. Washington Ave., Madison, WI, 53703-2637, USA.ORCID http://orcid.org/0000-0003-1050-0327
Flavia Del VecchioDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0003-4764-384X
Davide MartelliDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0001-6523-9598
Emanuele PerezDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0002-5382-4682
Domenico TuponeDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0002-4238-1011
Giovanni ZamboniDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0002-5329-5848
Roberto AmiciDepartment of Biomedical and NeuroMotor Sciences, University of Bologna, Piazza di Porta San Donato, 2, 40126, Bologna, Italy.ORCID http://orcid.org/0000-0002-9692-2215
University of Bologna · ITInstitut de Médecine Tropicale du Service de Santé des Armées · FROregon Health & Science University · USThe University of Melbourne · AUUniversity of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A cellular degeneration of two thalamic nuclei belonging to the "limbic thalamus", i.e., the anteroventral (AV) and mediodorsal (MD) nuclei, has been shown in patients suffering from Fatal Familial Insomnia (FFI), a lethal prion disease characterized by autonomic activation and severe insomnia. To better assess the physiological role of these nuclei in autonomic and sleep regulation, c-Fos expression was measured in rats during a prolonged exposure to low ambient temperature (T

Indexed as

AnimalsAnterior Thalamic NucleiAutonomic Nervous SystemBody Temperature RegulationElectroencephalographyMaleMediodorsal Thalamic NucleusMidline Thalamic NucleiProto-Oncogene Proteins c-fosRatsRats, Sprague-DawleySleep, REMSleep, Slow-WaveSleep StagesWakefulnessProto-Oncogene Proteins c-fosAutonomic regulationCold exposureFatal familial insomniaP-CREBSleep deprivation

Identifiers

PMID30887077
OpenAlexW2921610653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.