ArticleKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2020
Post-traumatic osteoarthritis diagnosed within 5 years following ACL reconstruction.
Article in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- History of anterior cruciate ligament reconstruction does not increase the risk of postoperative complications following total knee arthroplasty: a systematic review and meta-analysis.International orthopaedics · 2025Pooled it
- An Evidence-Based Systematic Review of Human Knee Post-Traumatic Osteoarthritis (PTOA): Timeline of Clinical Presentation and Disease Markers, Comparison of Knee Joint PTOA Models and Early Disease Implications.International journal of molecular sciences · 2021Pooled it
- Effects of Initial Graft Tension and Patient Sex on Knee Osteoarthritis Outcomes After ACL Reconstruction: A Randomized Controlled Clinical Trial With 10- to 12-Year Follow-up.The American journal of sports medicine · 2022Trial
- Two-year outcomes following concomitant ACL and extra-articular ligament reconstruction: a nationwide analysis of over 5,000 patients.Archives of orthopaedic and trauma surgery · 2026Article
- Early-Phase Quadriceps Activation After Knee Surgery: A Narrative Review of Current Rehabilitation Interventions and Identification of an Unmet Clinical Need.Journal of clinical medicine · 2026Review
- Associations Between Patient Characteristics and Cartilage T1ρ Relaxation Times Vary Over Time Following Patellar Dislocation.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2026Article
- Synovial Fluid Biomarkers Associated With Anterior Cruciate Ligament Injury and Reconstruction: A Systematic Review.Orthopaedic journal of sports medicine · 2026Review
- Arthrokinematic Analysis of High-Impact and Large-Rotation Activities at 1 to 2 Years After Anterior Cruciate Ligament Reconstruction and Meniscal Surgery.Orthopaedic journal of sports medicine · 2026Article
- Factors Associated With Functional Outcomes in Former Professional American-Style Football Players With Symptomatic Knee and Hip Osteoarthritis.Orthopaedic journal of sports medicine · 2026Article
- Role of Prokineticin-2 and Cytokines in Synovial Fluid in Traumatic Anterior Cruciate Ligament Injuries.Mediators of inflammation · 2026Article
- Relationship between Changes in Physical Activity and Knee Health 18 Months after ACL Reconstruction.Medicine and science in sports and exercise · 2025Article
- Articular Cartilage Arthrokinematics and Compositional Measurements With qMRI 1 to 2 Years After ACL Reconstruction With Meniscal Surgery.The American journal of sports medicine · 2025Article
- Patellofemoral Cartilage Degradation Based on T1ρ Relaxation Times Varies Inversely With BMI After Patellar Dislocation.Orthopaedic journal of sports medicine · 2025Article
- Using the Single-Leg Hop Test to Determine Knee Extension Strength After Anterior Cruciate Ligament Reconstruction.Orthopaedic journal of sports medicine · 2025Article
- Incidence and Risk Factors for Posttraumatic Osteoarthritis After Primary ACL Reconstruction in Pediatric Patients: A National Database Study.Orthopaedic journal of sports medicine · 2025Article
- Integrating Modern Technologies into Traditional Anterior Cruciate Ligament Tissue Engineering.Bioengineering (Basel, Switzerland) · 2025Review
- Anatomic Risk Factors for Initial and Secondary Noncontact Anterior Cruciate Ligament Injury: A Prospective Cohort Study in 880 Female Elite Handball and Soccer Players.The American journal of sports medicine · 2025Article
- Cumulative Impact Loading and Cartilage Synthesis Biomarkers May Be Associated With Injury Risk in Female Collegiate Basketball Players.Arthroscopy, sports medicine, and rehabilitation · 2024Article
- Review
- Vitamin D Deficiency after Anterior Cruciate Ligament Reconstruction Associates with Knee Osteoarthritis: A Retrospective Study.Nutrients · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose was to calculate the incidence of osteoarthritis in individuals following Anterior Cruciate Ligament Reconstruction (ACLR) in a large, national database and to examine the risk factors associated with OA development.
methodsA commercially available insurance database was queried to identify new diagnoses of knee OA in patients with ACLR. The cumulative incidence of knee OA diagnoses in patients after ACLR was calculated and stratified by time from reconstruction. Odds ratios were calculated using logistic regression to describe factors associated with a new OA diagnosis including age, sex, BMI, meniscus involvement, osteochondral graft use, and tobacco use.
resultsA total of 10,565 patients with ACLR were identified that did not have an existing diagnosis of OA, 517 of which had a documented new diagnosis of knee OA 5 years after ACL reconstruction. When stratified by follow-up time points, the incidence of a new OA diagnosis within 6 months was 2.3%; within a 1-year follow-up was 4.1%; within 2 years, follow-up was 6.2%, within 3 years, follow-up was 8.4%; within 4 years, follow-up was 10.4%; and within 5 years, follow-up was 12.3%. Risk factors for new OA diagnoses were age (OR 2.44, P < 0.001), sex (OR 1.2, P = 0.002), obesity (OR 1.4, P < 0.001), tobacco use (OR = 1.3, P = 0.001), and meniscal involvement (OR 1.2, P = 0.005).
conclusionApproximately 12% of patients presenting within 5 years following ACLR are diagnosed with OA. Demographic factors associated with an increased risk of a diagnosis of PTOA within 5 years after ACLR are age, sex, BMI, tobacco use, and concomitant meniscal surgery. Clinicians should be cognizant of these risk factors to develop risk profiles in patients with the common goal to achieve optimal long-term outcomes after ACLR. LEVEL OF EVIDENCE: III.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.