Evidence map›Paper›PMID 30887013›Full record

ArticleProceedings of the ... IEEE International Symposium on Signal Processing and Information Technology. IEEE International Symposium on Signal Processing and Information Technology2017

An Ensemble Feature Selection Method for Biomarker Discovery.

Aliasghar Shahrjooihaghighi, Hichem Frigui, Xiang Zhang, Xiaoli Wei, Biyun Shi, Ameni Trabelsi

Abstract read
In one paragraph

Article in Proceedings of the ... IEEE International Symposium on Signal Processing and Information Technology. IEEE International Symposium on Signal Processing and Information Technology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Precision Medicine Approaches with Metabolomics and Artificial Intelligence.International journal of molecular sciences · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Supervised Methods for Biomarker Detection from Microarray Experiments.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  11. Article
  12. Article
  13. Rapid Solution-Phase Hydrogen/Deuterium Exchange for Metabolite Compound Identification.Journal of the American Society for Mass Spectrometry · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aliasghar ShahrjooihaghighiDepartment of Computer Engineering and Computer Science, University of Louisville, Louisville, KY 40292, USA.
Hichem FriguiDepartment of Computer Engineering and Computer Science, University of Louisville, Louisville, KY 40292, USA.
Xiang ZhangDepartment of Chemistry, University of Louisville, Louisville, KY 40292, USA.
Xiaoli WeiDepartment of Chemistry, University of Louisville, Louisville, KY 40292, USA.
Biyun ShiDepartment of Chemistry, University of Louisville, Louisville, KY 40292, USA.
Ameni TrabelsiDepartment of Computer Engineering and Computer Science, University of Louisville, Louisville, KY 40292, USA.

Funding

Role of oxidized linoleic acid metabolites in the pathogenesis of alcoholic liver diseaseP20GM113226 · NIGMS · UNIVERSITY OF LOUISVILLE · PI GHARE, SMITA S · 2016 to 2025
$24.1M
The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · PI SHIRISH S BARVE · 2016 to 2026
$17.9M
Novel Therapies for Alcoholic HepatitisU01AA021893 · NIAAA · CLEVELAND CLINIC LERNER COM-CWRU · PI MCCLAIN, CRAIG J., MCCULLOUGH, ARTHUR JOSEPH · 2012 to 2017
$6.0M
Oxidized Metabolites of Linoleic Acid in Alcohol-induced Liver InjuryU01AA022489 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FELDSTEIN, ARIEL, MCCLAIN, CRAIG J. · 2014 to 2018
$1.7M
Mechanisms for alcohol induced gut barrier dysfunction in ALDR01AA023681 · NIAAA · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2014 to 2018
$1.6M
Novel therapies in alcoholic hepatitis University of LouisvilleU01AA021901 · NIAAA · UNIVERSITY OF LOUISVILLE · PI MCCLAIN, CRAIG J. · 2012 to 2017
$1.5M
Ultra Performance Liquid Chromatography High Resolution High Mass Accuracy Mass SpectrometerS10OD020106 · OD · UNIVERSITY OF LOUISVILLE · PI ZHANG, XIANG · 2015 to 2015
$600k
NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R01 AA023681NIAAA NIH HHS U01 AA021893NIAAA NIH HHS U01 AA021901NIAAA NIH HHS U01 AA022489NIGMS NIH HHS P20 GM113226NIH HHS S10 OD020106
6 · The paper itself

Abstract

Feature selection in Liquid Chromatography-Mass Spectrometry (LC-MS)-based metabolomics data (biomarker discovery) have become an important topic for machine learning researchers. High dimensionality and small sample size of LC-MS data make feature selection a challenging task. The goal of biomarker discovery is to select the few most discriminative features among a large number of irreverent ones. To improve the reliability of the discovered biomarkers, we use an ensemble-based approach. Ensemble learning can improve the accuracy of feature selection by combining multiple algorithms that have complementary information. In this paper, we propose an ensemble approach to combine the results of filter-based feature selection methods. To evaluate the proposed approach, we compared it to two commonly used methods, t-test and PLS-DA, using a real data set.

Indexed as

biomarker discoveryensemble feature selectionensemble learningfilter methodsscoring functions

Identifiers

PMID30887013
PMCPMC6420823

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.