Evidence map›Paper›PMID 30886982›Full record

ReviewBMC rheumatology2018

The extra-articular impacts of rheumatoid arthritis: moving towards holistic care.

I C Scott, A Machin, C D Mallen, S L Hider

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in BMC rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Gait disturbances in patients with rheumatoid arthritis.Archives of medical science : AMS · 2024
    Article
  14. Immunomodulatory effect ofThe journal of venomous animals and toxins including tropical diseases · 2024
    Article
  15. Observational
  16. Article
  17. Review
  18. Depression and Pain: Use of Antidepressants.Current neuropharmacology · 2022
    Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

I C Scott1Research Institute for Primary Care & Health Sciences, Primary Care Sciences, Keele University, Newcastle-under-Lyme, Staffordshire UK.ORCID 0000-0002-1268-9808
A Machin1Research Institute for Primary Care & Health Sciences, Primary Care Sciences, Keele University, Newcastle-under-Lyme, Staffordshire UK.
C D Mallen1Research Institute for Primary Care & Health Sciences, Primary Care Sciences, Keele University, Newcastle-under-Lyme, Staffordshire UK.
S L Hider1Research Institute for Primary Care & Health Sciences, Primary Care Sciences, Keele University, Newcastle-under-Lyme, Staffordshire UK.
Haywood Community Hospital · GBKeele University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although treat-to-target has revolutionised the outcomes of patients with rheumatoid arthritis (RA) there is emerging evidence that attaining the target of remission is insufficient to normalise patients' quality of life, and ameliorate the extra-articular impacts of RA. RA has a broad range of effects on patient's lives, with four key "extra-articular" impacts being pain, depression and anxiety, fatigue and rheumatoid cachexia. All of these are seen frequently; for example, studies have reported that 1 in 4 patients with RA have high-levels of fatigue. Commonly used drug treatments (including simple analgesics, non-steroidal anti-inflammatory drugs and anti-depressants) have, at most, only modest benefits and often cause adverse events. Psychological strategies and dynamic and aerobic exercise all reduce issues like pain and fatigue, although their effects are also only modest. The aetiologies of these extra-articular impacts are multifactorial, but share overlapping components. Consequently, patients are likely to benefit from management strategies that extend beyond the assessment and treatment of synovitis, and incorporate more broad-based, or "holistic", assessments of the extra-articular impacts of RA and their management, including non-pharmacological approaches. Innovative digital technologies (including tablet and smartphone "apps" that directly interface with hospital systems) are increasingly available that can directly capture patient-reported outcomes during and between clinic visits, and include them within electronic patient records. These are likely to play an important future role in delivering such approaches.

Indexed as

CachexiaFatigueMental healthPainRheumatoid arthritis

Identifiers

PMID30886982
PMCPMC6390577
OpenAlexW2897533936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.