Evidence map›Paper›PMID 30886979›Full record

ArticleBMC rheumatology2018

Demography, baseline disease characteristics, and treatment history of psoriasis patients with self-reported psoriatic arthritis enrolled in the PSOLAR registry.

Arthur Kavanaugh, Kim Papp, Alice B Gottlieb, Elke M G J de Jong, Soumya D Chakravarty, Shelly Kafka, Wayne Langholff, Kamyar Farahi, Bhaskar Srivastava, Jose U Scher

Registry-linked trialAbstract read
In one paragraph

Article in BMC rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00508547 (A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00508547 active not recruitingnot on this map

A Multicenter, Open Registry of Patients With Plaque Psoriasis Who Are Candidates for Systemic Therapy Including Biologics

Typeobservational_patient_registrySponsorJanssen Scientific Affairs, LLCRan2007 to 2030Enrolled20,167ConditionsPsoriasis
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Arthur Kavanaugh1Division of Rheumatology, Allergy and Immunology, Department of Medicine, University of California, San Diego, CA USA.
Kim Papp2K Papp Clinical Research and Probity Medical Research Inc., Waterloo, ON Canada.
Alice B Gottlieb3New York Medical College, Metropolitan Hospital, New York, NY USA.
Elke M G J de JongDepartment of Dermatology, Radboud University Medical Center, and Radboud University, Nijmegen, The Netherlands.
Soumya D Chakravarty5Janssen Scientific Affairs, LLC, Horsham, PA USA.
Shelly Kafka5Janssen Scientific Affairs, LLC, Horsham, PA USA.
Wayne Langholff7Janssen Research & Development, LLC, Spring House, PA USA.
Kamyar Farahi5Janssen Scientific Affairs, LLC, Horsham, PA USA.
Bhaskar Srivastava5Janssen Scientific Affairs, LLC, Horsham, PA USA.
Jose U Scher8Division of Rheumatology, New York University School of Medicine and Hospital for Joint Diseases, 301 East 17th Street, Room 1608, New York, NY 10003 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo evaluate demographics, family history, and previous medication use at enrollment in a subset of psoriasis patients with self-reported psoriatic arthritis (PsA) enrolled in Psoriasis Longitudinal Assessment and Registry (PSOLAR).

methodsPSOLAR is an international, prospective, longitudinal, disease-based registry that collects data in patients receiving, or are eligible to receive, systemic or biologic treatments for psoriasis. Baseline demographic, disease characteristics, medical history, and prior medication use at enrollment were evaluated in PSOLAR psoriasis patients self-reporting PsA (

resultsAt enrollment, demographic characteristics were distinct between psoriasis patients self-reporting PsA and psoriasis only patients. Of the patients with psoriasis self-reporting PsA, 44.4% had cardiovascular disease (CVD), 26.3% had psychiatric illness, and 3.2% had inflammatory bowel disease (IBD), with each more prevalent than among patients with psoriasis only (

conclusionsDemographics, family history, and previous medication use were generally comparable between "PsA established by a HCP" patients and psoriasis patients self-reporting PsA in the PSOLAR registry, but there were statistical differences compared with the psoriasis only group regarding the prevalence of certain comorbidities (CVD, psychiatric illness, and IBD). These analyses provide important data regarding characteristics of psoriasis patients with self-reported PsA in PSOLAR.

trial registrationNCT00508547.

Indexed as

DemographyPSOLARPsoriasisPsoriatic arthritis

Identifiers

PMID30886979
PMCPMC6390609

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.