Evidence map›Paper›PMID 30886967›Full record

ArticleBMC rheumatology2018

Pain, sleep and emotional well-being explain the lack of agreement between physician- and patient-perceived remission in early rheumatoid arthritis.

Samina A Turk, Linda A Rasch, Dirkjan van Schaardenburg, Willem F Lems, Marjolein Sanberg, Lilian H D van Tuyl, Marieke M Ter Wee

Open access · goldAbstract read
In one paragraph

Article in BMC rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Patient-reported outcome measures applied in chronic diseases relevant to asthma remission: a scoping review.European respiratory review : an official journal of the European Respiratory Society · 2026
    Article
  2. Review
  3. Non-inflammatory pain in inflammatory arthritis.Rheumatology (Oxford, England) · 2023
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Samina A TurkDepartment of Rheumatology, Amsterdam Rheumatology and immunology Center | Reade, PO box 58271, 1040 HG, Amsterdam, The Netherlands.ORCID 0000-0003-1448-0140
Linda A Rasch2Department of Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands.
Dirkjan van SchaardenburgDepartment of Rheumatology, Amsterdam Rheumatology and immunology Center | Reade, PO box 58271, 1040 HG, Amsterdam, The Netherlands.
Willem F LemsDepartment of Rheumatology, Amsterdam Rheumatology and immunology Center | Reade, PO box 58271, 1040 HG, Amsterdam, The Netherlands.
Marjolein SanbergDepartment of Rheumatology, Amsterdam Rheumatology and immunology Center | Reade, PO box 58271, 1040 HG, Amsterdam, The Netherlands.
Lilian H D van Tuyl2Department of Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands.
Marieke M Ter Wee2Department of Rheumatology, Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands.
Amsterdam UMC Location Vrije Universiteit Amsterdam · NLReade · NLAmsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundClinical response and remission are defined in multiple ways and measured with different instruments, resulting in substantial variation of the proportion of patients classified as being in remission. Therefore, the agreement between patient-perceived, physician-perceived remission and clinical response and remission definitions was determined in early rheumatoid arthritis (RA) patients. And secondly, differences in clinical and patient-reported outcomes, in patients in physician-perceived remission, between patients in and not in self-perceived remission were assessed.

methodsIn 84 early RA patients, who received methotrexate and glucocorticoids, DAS44, ACR/EULAR Boolean-based remission, EULAR good and ACR70 response were determined after 12 weeks. Agreement between patient-perceived (phrased: "

resultsAgreement between the assessed outcome measures differed enormously. The agreement between physician-perceived and patient-perceived remission was 64% (kappa 0.25,

conclusionOne-third of the early RA patients disagreed with the physician on being in remission. Those patients had less improvement on RAID components, especially on pain, sleep and emotional well-being. Together with the variability in clinical response and remission definitions, these results highlight the need to increase patient involvement in their own health care decisions.

Indexed as

Disease-modifying antirheumatic drugs (Dmards)FatiguePatient reported outcomesPhysician agreementRheumatoid arthritis

Identifiers

PMID30886967
PMCPMC6390551
OpenAlexW2805049163

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.