Evidence map›Paper›PMID 30886958›Full record

ArticleBMC rheumatology2018

High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility.

Adel M Al-Awadhi, Mohammad Z Haider, Jalaja Sukumaran, Sowmya Balakrishnan

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC rheumatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Adel M Al-Awadhi1Department of Medicine, Faculty of Medicine, Kuwait University, Jabriya, Kuwait.
Mohammad Z Haider3Department of Pediatrics, Faculty of Medicine, Kuwait University, P. O. Box 24923, 13110 Safat, Kuwait.ORCID 0000-0002-8187-0061
Jalaja Sukumaran3Department of Pediatrics, Faculty of Medicine, Kuwait University, P. O. Box 24923, 13110 Safat, Kuwait.
Sowmya Balakrishnan3Department of Pediatrics, Faculty of Medicine, Kuwait University, P. O. Box 24923, 13110 Safat, Kuwait.
Kuwait University · KWAmiri Hospital · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSystemic lupus erythematosus (SLE) is an autoimmune inflammatory disease which involves the loss of self-tolerance with hyperactivation of autoreactive T- and B-cells. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) encodes for lymphoid specific phosphatase (LYP) which is a key negative regulator of T lymphocyte activation. The aim of this study was to investigate the association between

methodsThe study included 134 SLE patients and 214 controls from Kuwait. The genotypes of

resultsA relatively high prevalence of the variant 620 W (T-allele) of the

conclusionsThe frequency of

Indexed as

Functional variantGeneKuwaitProtein tyrosine phosphatase non receptor-22Systemic lupus erythematosus

Identifiers

PMID30886958
PMCPMC6390595
OpenAlexW2799813994

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.