Evidence map›Paper›PMID 30886906›Full record

ArticleCommunications biology2019

Identification of evolutionarily conserved virulence factor by selective pressure analysis of

Masaya Yamaguchi, Kana Goto, Yujiro Hirose, Yuka Yamaguchi, Tomoko Sumitomo, Masanobu Nakata, Kazuhiko Nakano, Shigetada Kawabata

Open access · goldAbstract read
In one paragraph

Article in Communications biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 33 citations in OpenAlex.

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  11. Editorial: Host-Pathogen Interactions During Pneumococcal Infection.Frontiers in cellular and infection microbiology · 2021
    Article
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  16. Communications biology · 2019
    Article
  17. Frontiers in cellular and infection microbiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Masaya YamaguchiDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan. yamaguchi@dent.osaka-u.ac.jp.ORCID http://orcid.org/0000-0001-6218-7112
Kana GotoDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Yujiro HiroseDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Yuka YamaguchiDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Tomoko SumitomoDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Masanobu NakataDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Kazuhiko NakanoDepartment of Pediatric Dentistry, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
Shigetada KawabataDepartment of Oral and Molecular Microbiology, Osaka University Graduate School of Dentistry, Suita, Osaka, 565-0871, Japan.
The University of Osaka · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolutionarily conserved virulence factors can be candidate therapeutic targets or vaccine antigens. Here, we investigated the evolutionary selective pressures on 16 pneumococcal choline-binding cell-surface proteins since

Indexed as

Biological EvolutionSelection, GeneticAmino Acid SequenceBacterial ProteinsCodonMutationOpen Reading FramesPhylogenyPneumococcal InfectionsStreptococcus pneumoniaeVirulence FactorsBacterial ProteinsCodonVirulence Factors

Identifiers

PMID30886906
PMCPMC6408437
OpenAlexW2950326982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.