ArticleFrontiers in bioengineering and biotechnology2019
Metabolic Engineering and Synthetic Biology: Synergies, Future, and Challenges.
Article in Frontiers in bioengineering and biotechnology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.
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Who cites it
31 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Leveraging AI for cell biology discovery.Biochemical Society transactions · 2026Review
- Biotechnological Applications of Bacteria.Progress in molecular and subcellular biology · 2026Review
- Engineering bacterial cell morphology for the design of robust cell factories.Biochemistry and biophysics reports · 2025Review
- Computational Strategies to Enhance Vitamin BCurrent microbiology · 2025Review
- Review
- Enhancing Withanolide Production in thePlants (Basel, Switzerland) · 2024Review
- Designing a safer circular economy of chemicals.Clean technologies and environmental policy · 2024Article
- Cyberbiosecurity: Advancements in DNA-based information security.Biosafety and health · 2024Review
- Super-pigment: Deciphering shikonin biosynthesis to fight cancer, inflammation, and much more.Plant physiology · 2024Article
- Machine Learning to Predict Enzyme-Substrate Interactions in Elucidation of Synthesis Pathways: A Review.Metabolites · 2024Review
- Recent Advances in Cell Membrane Coated-Nanoparticles as Drug Delivery Systems for Tackling Urological Diseases.Pharmaceutics · 2023Review
- The chromosome-scale genome assembly of cluster bean provides molecular insight into edible gum (galactomannan) biosynthesis family genes.Scientific reports · 2023Article
- Cell Membrane Biomimetic Nanoparticles with Potential in Treatment of Alzheimer's Disease.Molecules (Basel, Switzerland) · 2023Review
- Application of GeneCloudOmics: Transcriptomic Data Analytics for Synthetic Biology.Methods in molecular biology (Clifton, N.J.) · 2023Article
- Microalgae in Bioplastic Production: A Comprehensive Review.Arabian journal for science and engineering · 2023Review
- Metabolic pathways engineering for drought or/and heat tolerance in cereals.Frontiers in plant science · 2023Review
- A Single-Component Blue Light-Induced System Based on EL222 inInternational journal of molecular sciences · 2022Article
- Application of metabolic engineering to enhance the content of alkaloids in medicinal plants.Metabolic engineering communications · 2022Review
- Strain design optimization using reinforcement learning.PLoS computational biology · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The "-omics" era has brought a new set of tools and methods that have created a significant impact on the development of Metabolic Engineering and Synthetic Biology. These fields, rather than working separately, depend on each other to prosper and achieve their individual goals. Synthetic Biology aims to design libraries of genetic components (promoters, coding sequences, terminators, transcriptional factors and their binding sequences, and more), the assembly of devices, genetic circuits and even organism; in addition to obtaining quantitative information for the creation of models that can predict the behavior of biological systems (Cameron et al., 2014). Metabolic engineering seeks for the optimization of cellular processes, endemic to a specific organism, to produce a compound of interest from a substrate, preferably cheap and simple. It uses different databases, libraries of components and conditions to generate the maximum production rate of a desired chemical compound and avoiding inhibitors and conditions that affect the growth rate and other vital functions in the specific organism to achieve these goals; metabolic fluxes manipulation represents an important alternative (Stephanopoulos, 2012).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.