Evidence map›Paper›PMID 30886687›Full record

ArticleJournal of tissue engineering

Osteogenic potential of mesenchymal stem cells from rat mandible to regenerate critical sized calvarial defect.

Dong Joon Lee, Jane Kwon, Luke Current, Kun Yoon, Rahim Zalal, Xiangxiang Hu, Peng Xue, Ching-Chang Ko

Abstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. PTH1R Suppressed Apoptosis of Mesenchymal Progenitors in Mandibular Growth.International journal of molecular sciences · 2024
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Regional variations of jaw bone characteristics in an ovariectomized rat model.Journal of the mechanical behavior of biomedical materials · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dong Joon LeeOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.ORCID https://orcid.org/0000-0002-9284-0773
Jane KwonOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Luke CurrentOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Kun YoonOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Rahim ZalalOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Xiangxiang HuOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Peng XueOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ching-Chang KoOral and Craniofacial Health Sciences Research and North Carolina Oral Health Institute, School of Dentistry, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

Funding

Engineering novel bio-inspired materials for stem-cell mediated bone regenerationR01DE022816 · NIDCR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KO, CHING-CHANG · 2014 to 2018
$2.0M
NIDCR NIH HHS R01 DE022816
6 · The paper itself

Abstract

Although bone marrow-derived mesenchymal stem cells (MSCs) have been extensively explored in bone tissue engineering, only few studies using mesenchymal stem cells from mandible (M-MSCs) have been reported. However, mesenchymal stem cells from mandible have the potential to be as effective as femur-derived mesenchymal stem cells (F-MSCs) in regenerating bone, especially in the orofacial regions, which share embryonic origin, proximity, and accessibility. M-MSCs were isolated and characterized using mesenchymal stem cell-specific markers, colony forming assay, and multi-potential differentiation.

Indexed as

craniofacial bone tissue engineeringcritical sized defectmandibleMesenchymal stem cells from mandible

Identifiers

PMID30886687
PMCPMC6415471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.