Evidence map›Paper›PMID 30886671›Full record

ArticleOxidative medicine and cellular longevity2019

Enhancement by Hydrogen Peroxide of Calcium Signals in Endothelial Cells Induced by 5-HT1B and 5-HT2B Receptor Agonists.

Pavel V Avdonin, Alexander D Nadeev, Galina Yu Mironova, Irina L Zharkikh, Piotr P Avdonin, Nikolay V Goncharov

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Synergistic Interaction of 5-HTInternational journal of molecular sciences · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Reactive Oxygen Species and Endothelial CaInternational journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Pavel V AvdoninKoltsov Institute of Developmental Biology RAS, Moscow, Russia.ORCID 0000-0002-4138-1589
Alexander D NadeevSechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint Petersburg, Russia.
Galina Yu MironovaKoltsov Institute of Developmental Biology RAS, Moscow, Russia.ORCID 0000-0002-3698-7682
Irina L ZharkikhInstitute of General Pathology and Pathophysiology RAMS, Moscow, Russia.
Piotr P AvdoninKoltsov Institute of Developmental Biology RAS, Moscow, Russia.
Nikolay V GoncharovSechenov Institute of Evolutionary Physiology and Biochemistry RAS, Saint Petersburg, Russia.ORCID 0000-0002-5452-2125
Koltzov Institute of Developmental Biology · RUInstitute of Evolutionary Physiology and Biochemistry · RUResearch Institute of General Pathology and Pathophysiology, the Russian Academy of Medical Sciences · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen peroxide, formed in the endothelium, acts as a factor contributing to the relaxation of blood vessels. The reason for this vasodilatory effect could be modulation by H

Indexed as

AcetylcysteineBenzoxazolesCalciumCalcium SignalingFluorescenceHumansHuman Umbilical Vein Endothelial CellsHydrogen PeroxideIndolesQuinoxalinesReceptor, Serotonin, 5-HT1BReceptor, Serotonin, 5-HT2BSerotonin 5-HT1 Receptor AgonistsSerotonin 5-HT2 Receptor AgonistsThiophenesTriazoles1-(5-(2-thenyloxy)-1H-indol-3-yl)propan-2-amine3-benzyl-7-(2-benzoxazolyl)thio-1,2,3-triazolo(4,5-d)pyrimidineAcetylcysteineBenzoxazolesCalciumCGS 12066BHydrogen PeroxideIndolesQuinoxalinesReceptor, Serotonin, 5-HT1BReceptor, Serotonin, 5-HT2BSerotonin 5-HT1 Receptor AgonistsSerotonin 5-HT2 Receptor AgonistsThiophenesTriazolesVanadates

Identifiers

PMID30886671
PMCPMC6388333
OpenAlexW2914200949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.