ArticleFrontiers in human neuroscience2019
Real-Time fMRI Neurofeedback in Patients With Tobacco Use Disorder During Smoking Cessation: Functional Differences and Implications of the First Training Session in Regard to Future Abstinence or Relapse.
Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Cue-Elicited Brain Activity and Treatment Outcomes in Substance Use Disorders: A Meta-Analysis.JAMA network open · 2025Pooled it
- Self-navigating the "Island of Reil": a systematic review of real-time fMRI neurofeedback training of insula activity.Translational psychiatry · 2025Pooled it
- Frontostriatal circuitry as a target for fMRI-based neurofeedback interventions: A systematic review.Frontiers in human neuroscience · 2022Pooled it
- Predictors of neurofeedback training outcome: A systematic review.NeuroImage. Clinical · 2020Pooled it
- A systematic review of fMRI neurofeedback reporting and effects in clinical populations.NeuroImage. Clinical · 2020Pooled it
- Correlations Between the DMN and the Smoking Cessation Outcome of a Real-Time fMRI Neurofeedback Supported Exploratory Therapy Approach: Descriptive Statistics on Tobacco-Dependent Patients.Clinical EEG and neuroscience · 2022Trial
- Functional and clinical outcomes of FMRI-based neurofeedback training in patients with alcohol dependence: a pilot study.European archives of psychiatry and clinical neuroscience · 2022Trial
- Peer-guided movie neurofeedback to facilitate recovery in opioid use disorder.medRxiv : the preprint server for health sciences · 2026Article
- Regulation of craving for real-time fMRI neurofeedback based on individual classification.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024Article
- Neuroimaging Biomarkers in Addiction.medRxiv : the preprint server for health sciences · 2024Article
- Closing the loop between brain and electrical stimulation: towards precision neuromodulation treatments.Translational psychiatry · 2023Review
- Thalamic volume and functional connectivity are associated with nicotine dependence severity and craving.Addiction biology · 2023Article
- Neurofeedback-dependent influence of the ventral striatum using a working memory paradigm targeting the dorsolateral prefrontal cortex.Frontiers in behavioral neuroscience · 2023Article
- Cue-reactivity targeted smoking cessation intervention in individuals with tobacco use disorder: a scoping review.Frontiers in psychiatry · 2023Article
- Individual- and Connectivity-Based Real-Time fMRI Neurofeedback to Modulate Emotion-Related Brain Responses in Patients with Depression: A Pilot Study.Brain sciences · 2022Article
- Disentangling craving- and valence-related brain responses to smoking cues in individuals with nicotine use disorder.Addiction biology · 2022Article
- Smoking-induced craving relief relates to increased DLPFC-striatal coupling in nicotine-dependent women.Drug and alcohol dependence · 2021Article
- Baclofen-induced Changes in the Resting Brain Modulate Smoking Cue Reactivity: A Double-blind Placebo-controlled Functional Magnetic Resonance Imaging Study in Cigarette Smokers.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2020Article
- Comparison of neural signal sources for discriminating "crave" and "don't crave" task conditions: Implications for fMRI neurofeedback.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most prominent symptoms in addiction disorders is the strong desire to consume a particular substance or to show a certain behavior (craving). The strong association between craving and the probability of relapse emphasizes the importance of craving in the therapeutic process. Former studies have demonstrated that neuromodulation using real-time fMRI (rtfMRI) neurofeedback (NF) can be used as a treatment modality in patients with tobacco use disorder. The aim of the present project was to determine whether it is possible to predict the outcome of NF training plus group psychotherapy at the beginning of the treatment. For that purpose, neuronal responses during the first rtfMRI NF session of patients who remained abstinent for at least 3 months were compared to those of patients with relapse. All patients were included in a certified smoke-free course and took part in three NF sessions. During the rtfMRI NF sessions tobacco-associated and neutral pictures were presented. Subjects were instructed to reduce their neuronal responses during the presentation of smoking cues in an individualized region of interest for craving [anterior cingulate cortex (ACC), insula or dorsolateral prefrontal cortex]. Patients were stratified to different groups [abstinence (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.