Evidence map›Paper›PMID 30886568›Full record

ReviewFrontiers in neuroscience2019

Responses of Plasma Catecholamine, Serotonin, and the Platelet Serotonin Transporter to Cigarette Smoking.

Curtis Lee Lowery, Donna Woulfe, Fusun Kilic

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 54 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Curtis Lee LoweryDepartments of Biochemistry and Molecular Biology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
Donna WoulfeDepartment of Biological Sciences, University of Delaware, Newark, DE, United States.
Fusun KilicDepartments of Biochemistry and Molecular Biology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States.
University of Arkansas for Medical Sciences · USUniversity of Delaware · US

Funding

Communication between platelet SERT and plasma 5HTR01HL091196 · NHLBI · UNIV OF ARKANSAS FOR MED SCIS · PI KILIC, FUSUN · 2009 to 2014
$2.2M
Placental serotonin transporter uses ERp44 and Ero1-L for maturation.R03HD058697 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI KILIC, FUSUN · 2009 to 2010
$143k
Impact of Diabetes on Placental Serotonin TransporterR03HD053477 · NICHD · UNIV OF ARKANSAS FOR MED SCIS · PI KILIC, FUSUN · 2006 to 2007
$140k
NHLBI NIH HHS R01 HL091196NICHD NIH HHS R03 HD053477NICHD NIH HHS R03 HD058697
6 · The paper itself

Abstract

Cigarette smoking is one of the major causes of coronary heart disease with a thirty percent mortality rate in the United States. Cigarette smoking acting on the central nervous system (CNS) to stimulate the sympathetic nervous system (SNS) through, which facilitates the secretion of serotonin (5-HT) and catecholamines to supraphysiological levels in blood. The enhanced levels of 5-HT and catecholamines in smokers' blood are associated with increases in G protein-coupled receptor signaling and serotonylation of small GTPases, which in turn lead to remodeling of cytoskeletal elements to enhance granule secretion and promote unique expression of sialylated

Indexed as

catecholaminecigarette smokingplatelet aggregationserotoninserotonin transporter

Identifiers

PMID30886568
PMCPMC6409334
OpenAlexW2918617179

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.