ArticleJournal of Korean medical science2019
Effects of One-dose Varicella Vaccination on Disease Severity in Children during Outbreaks in Seoul, Korea.
Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Article
- The impact of the implementation of the two-dose varicella vaccine immunization strategy in Quzhou: A retrospective birth cohort study.Human vaccines & immunotherapeutics · 2024Article
- Estimation of single-dose varicella vaccine effectiveness in South Korea using mathematical modeling.Human vaccines & immunotherapeutics · 2022Article
- The comparison of seroconversion rates among different varicella vaccines administered Turkish children; MAV/06 and vOka.Human vaccines & immunotherapeutics · 2021Article
- Waning Effectiveness of One-dose Universal Varicella Vaccination in Korea, 2011-2018: a Propensity Score Matched National Population Cohort.Journal of Korean medical science · 2021Article
- Varicella Pneumonia in an Immunocompetent Young Adult in the Vaccine Era.Journal of Korean medical science · 2020Article
- Letter to the Editor: Epidemiological Comments on the Effectiveness of the Varicella Vaccine in Korea.Journal of Korean medical science · 2020Article
- A Centralized Outbreak of Varicella among Children Attending Preschool in Suzhou, China.BioMed research international · 2020Article
- Protection against Severe Varicella Disease.Journal of Korean medical science · 2019Article
- Increasing varicella incidence rates among children in the Republic of Korea: an age-period-cohort analysis.Epidemiology and infection · 2019Article
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn Korea, the incidence of varicella has increased despite the introduction of a universal one-dose vaccination for children aged 12-15 months in 2005. A previous study demonstrated that the vaccine effectiveness was insufficient to prevent against varicella. We assessed the effect of the varicella vaccination on disease severity.
methodsEpidemiologic investigation of varicella cases in Seoul metropolitan area from 2015 to 2017 were used. Varicella-related symptoms such as rash were determined by the clinical practitioners. Disease severity of patients was assessed by the number of skin lesions and divided into mild (≤ 50) and moderate (51-249) to severe (≥ 250). Unconditional logistic regression analysis was performed and age was controlled.
resultsAmong a total of 1,008 varicella cases reported, 869 cases were breakthrough cases and 139 were unvaccinated cases. The risk for occurrence of moderate-to-severe disease in the breakthrough group was 0.57 times less than that of the unvaccinated group.
conclusionThese data suggest that national varicella vaccination may have a significant effect on attenuation of disease severity in children.
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