Evidence map›Paper›PMID 30886549›Full record

ArticleJournal of Korean medical science2019

Pathological Characteristics of Prostate Cancer in Men Aged < 50 Years Treated with Radical Prostatectomy: a Multi-Centre Study in Korea.

Mun Su Chung, Myungsun Shim, Jin Seon Cho, Woojin Bang, Sun Il Kim, Sung Yong Cho, Koon Ho Rha, Sung Joon Hong, Kyo Chul Koo, Kwang Suk Lee and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of Korean medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mun Su ChungDepartment of Urology, International St. Mary's Hospital, Catholic Kwandong University, Incheon, Korea.ORCID https://orcid.org/0000-0002-9885-3559
Myungsun ShimDepartment of Urology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0003-2029-9081
Jin Seon ChoDepartment of Urology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0003-0429-191X
Woojin BangDepartment of Urology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Chuncheon, Korea.ORCID https://orcid.org/0000-0002-1753-2623
Sun Il KimDepartment of Urology, Ajou University Hospital, Ajou University School of Medicine, Suwon, Korea.ORCID https://orcid.org/0000-0003-2674-983X
Sung Yong ChoDepartment of Urology, Inje University Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.ORCID https://orcid.org/0000-0002-4870-829X
Koon Ho RhaDepartment of Urology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-8588-7584
Sung Joon HongDepartment of Urology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9869-065X
Kyo Chul KooDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7303-6256
Kwang Suk LeeDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7961-8393
Byung Ha ChungDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9817-3660
Seung Hwan LeeDepartment of Urology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-7358-8544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecently, younger prostate cancer (PCa) patients have been reported to harbour more favourable disease characteristics after radical prostatectomy (RP) than older men. We analysed young men (<50 years) with PCa among the Korean population, paying attention to pathological characteristics on RP specimen and biochemical recurrence (BCR).

methodsThe multi-centre, Severance Urological Oncology Group registry was utilized to identify 622 patients with clinically localized or locally advanced PCa, who were treated with RP between 2001 and 2017. Patients were dichotomized into two groups according to age (< 50-year-old [n = 75] and ≥ 50-year-old [n = 547]), and clinicopathological characteristics were analysed. Propensity score matching was used when assessing BCR between the two groups.

resultsAlthough biopsy Gleason score (GS) was lower in younger patients (

conclusionContrary to prior reports, younger PCa patients did not have more favourable pathologic features on RP specimen and showed similar BCR rates compared to older men. These findings should be considered when making treatment decisions for young Korean patients with PCa.

Indexed as

Age FactorsDisease-Free SurvivalHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalPrognosisPropensity ScoreProstatectomyProstate-Specific AntigenProstatic NeoplasmsRegistriesRepublic of KoreaProstate-Specific AntigenPrognosisProstatectomyProstatic NeoplasmsYoung Adults

Identifiers

PMID30886549
PMCPMC6417998

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.