Evidence map›Paper›PMID 30886526›Full record

ArticleBiomarkers in cancer2019

RBBP6 Is Abundantly Expressed in Human Cervical Carcinoma and May Be Implicated in Its Malignant Progression.

Zodwa Dlamini, Thokozile Ledwaba, Rodney Hull, Sarala Naicker, Zukile Mbita

Open access · diamondAbstract read
In one paragraph

Article in Biomarkers in cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Zodwa DlaminiResearch, Innovation & Engagements Portfolio, Mangosuthu University of Technology, Durban, South Africa.
Thokozile LedwabaNational Institute for Communicable Diseases, Centre for HIV and STIs, Johannesburg, South Africa.
Rodney HullResearch, Innovation & Engagements Portfolio, Mangosuthu University of Technology, Durban, South Africa.
Sarala NaickerFaculty of Health Sciences, Wits Medical School, Parktown, South Africa.
Zukile MbitaDepartment of Biochemistry, Microbiology and Biotechnology, University of Limpopo, Sovenga, South Africa.
Mangosuthu University of Technology · ZANational Institute for Communicable DiseasesUniversity of Limpopo · ZAUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RBBP6 is a novel gene encoding splicing-associated proteins. There are 3 protein isoforms (isoforms 1-3). RBBP6 isoforms 1 has been shown to interact with both p53 and Rb. It also plays a role in the induction of apoptosis and the regulation of the cell cycle. The expression of RBBP6 has been documented in several cancers but RBBP6 expression in cervical cancer has not been well studied. The aim of this study was to establish expression levels and tissue distribution of the RBBP6 gene products at both protein and messenger RNA (mRNA) levels in cervical cancer by immunocytochemistry and

Indexed as

apoptosisCervical cancerRBBP6

Identifiers

PMID30886526
PMCPMC6415476
OpenAlexW2921127984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.