ArticleWorld journal of gastroenterology2019
Utility of linked color imaging for endoscopic diagnosis of early gastric cancer.
Article in World journal of gastroenterology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Diagnostic accuracy of linked color imaging and white light imaging for early gastric cancer and gastrointestinal metaplasia: a systematic review and meta-analysis.Frontiers in oncology · 2024Pooled it
- Article
- Observational
- Optimal upper gastrointestinal surveillance strategies for gastric, small bowel and pancreatic cancer detection in Lynch syndrome.Familial cancer · 2026Review
- Linked color imaging for detection and characterization of gastrointestinal neuroendocrine tumors.BMC gastroenterology · 2025Article
- Characteristics of Superficial Gastric Neoplasms Detected Not by White Light Imaging but by Linked Color Imaging.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- Topic highlight on texture and color enhancement imaging in gastrointestinal diseases.World journal of gastroenterology · 2024Article
- Higher detectability of gastric cancer afterDEN open · 2024Article
- L-Menthol for Color Difference Change Between Early Gastric Cancer and Surrounding Mucosa: A Prospective Study.Digestive diseases and sciences · 2024Article
- Article
- Clinical Usefulness of Linked Color Imaging for Detection and Characterization of UndifferentiatedType Early Gastric Cancer.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2023Article
- Linked Color Imaging for Stomach.Diagnostics (Basel, Switzerland) · 2023Review
- Current status and future perspective of linked color imaging for gastric cancer screening: a literature review.Journal of gastroenterology · 2023Review
- NOL6 Regulates the Proliferation and Apoptosis of Gastric Cancer CellsFrontiers in oncology · 2022Article
- Clinical Efficacy and Adverse Reactions of Bevacizumab plus Radiochemotherapy in the Treatment of Advanced Gastric Cancer.Journal of oncology · 2022Article
- [Screening of early gastric cancer using Pre-Activation Squeeze-and-Excitation ResNet].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021Article
- Diagnostic Ability of High-definition Imaging Using Ultraslim Endoscopes in Early Gastric Cancer.Journal of gastric cancer · 2021Article
- Collision Tumors of Gastric Adenocarcinoma and Mucosa-associated Lymphoid Tissue Lymphoma.Internal medicine (Tokyo, Japan) · 2021Article
- Recent advances in diagnostic upper endoscopy.World journal of gastroenterology · 2020Review
- RGB Pixel Brightness Characteristics of Linked Color Imaging in Early Gastric Cancer: A Pilot Study.Gastroenterology research and practice · 2020Article
Corrections and comments
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Authors and funding
14 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLinked color imaging (LCI) is a method of endoscopic imaging that emphasizes slight differences in red mucosal color.
aimTo evaluate LCI in diagnostic endoscopy of early gastric cancer and to compare LCI and pathological findings.
methodsEndoscopic images were obtained for 39 patients (43 lesions) with early gastric cancer. Three endoscopists evaluated lesion recognition with white light imaging (WLI) and LCI. Color values in Commission Internationale de l'Eclairage (CIE) 1976 L*a*b* color space were used to calculate the color difference (ΔE) between cancer lesions and non-cancer areas. After endoscopic submucosal dissection, blood vessel density in the surface layer of the gastric epithelium was evaluated pathologically. The identical region of interest was selected for analyses of endoscopic images (WLI and LCI) and pathological analyses.
resultsLCI was superior for lesion recognition (
conclusionLCI is more effective for recognition of early gastric cancer compared to WLI as a result of improved visualization of changes in redness. Surface blood vessel density was significantly higher in cancer lesions, and this result is consistent with LCI image analysis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.