Evidence map›Paper›PMID 30886369›Full record

ReviewNature ecology & evolution2019

Vector-borne transmission and evolution of Zika virus.

Gladys Gutiérrez-Bugallo, Luis Augusto Piedra, Magdalena Rodriguez, Juan A Bisset, Ricardo Lourenço-de-Oliveira, Scott C Weaver, Nikos Vasilakis, Anubis Vega-Rúa

Open access · bronzeAbstract readReview
In one paragraph

Review in Nature ecology & evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
19.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 153 citations in OpenAlex.

  1. Exploring the Mosquito-Arbovirus Network: A Survey of Vector Competence Experiments.The American journal of tropical medicine and hygiene · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Human Riboviruses: A Comprehensive Study.Journal of molecular evolution · 2025
    Review
  12. Article
  13. Dissecting Zika virus transmission byFrontiers in microbiology · 2025
    Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. An Overview of Zika Virus and Zika Virus Induced Neuropathies.International journal of molecular sciences · 2024
    Review
  19. Review
  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Gladys Gutiérrez-BugalloDepartment of Vector Control, Center for Research, Diagnostic and Reference, Institute of Tropical Medicine Pedro Kourí, PAHO-WHO Collaborating Center for Dengue and its Control, Havana, Cuba.
Luis Augusto PiedraDepartment of Vector Control, Center for Research, Diagnostic and Reference, Institute of Tropical Medicine Pedro Kourí, PAHO-WHO Collaborating Center for Dengue and its Control, Havana, Cuba.
Magdalena RodriguezDepartment of Vector Control, Center for Research, Diagnostic and Reference, Institute of Tropical Medicine Pedro Kourí, PAHO-WHO Collaborating Center for Dengue and its Control, Havana, Cuba.
Juan A BissetDepartment of Vector Control, Center for Research, Diagnostic and Reference, Institute of Tropical Medicine Pedro Kourí, PAHO-WHO Collaborating Center for Dengue and its Control, Havana, Cuba.
Ricardo Lourenço-de-OliveiraFundação Oswaldo Cruz-Fiocruz, Instituto Oswaldo Cruz, Laboratório de Mosquitos Transmissores de Hematozoários, Rio de Janeiro, Brazil.
Scott C WeaverDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX, USA.
Nikos VasilakisDepartment of Pathology, University of Texas Medical Branch, Galveston, TX, USA.ORCID http://orcid.org/0000-0002-0708-3289
Anubis Vega-RúaLaboratory of Vector Control Research, Unit Transmission Reservoir and Pathogen Diversity, Institute Pasteur of Guadeloupe, Les Abymes, Guadeloupe, France. avega@pasteur.fr.ORCID http://orcid.org/0000-0002-1670-5350
Instituto de Medicina Tropical “Pedro Kourí” · CUThe University of Texas Medical Branch at Galveston · USFundação Oswaldo Cruz · BRInstitut Pasteur de la Guadeloupe · GP

Funding

West African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1M
World Reference Center for Emerging Viruses and Arboviruses (WRCEVA)R24AI120942 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WEAVER, SCOTT C · 2016 to 2024
$8.5M
Mechanisms and Public Health Impact of Sylvatic Dengue Virus Emergence in BorneoU01AI115577 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI VASILAKIS, NIKOS · 2016 to 2019
$2.4M
NIAID NIH HHS R24 AI120942NIAID NIH HHS U01 AI115577NIAID NIH HHS U01 AI151801
6 · The paper itself

Abstract

Zika virus (ZIKV), discovered in the Zika Forest of Uganda in 1947, is a mosquito-borne flavivirus related to yellow fever, dengue and West Nile viruses. From its discovery until 2007, only sporadic ZIKV cases were reported, with mild clinical manifestations in patients. Therefore, little attention was given to this virus before epidemics in the South Pacific and the Americas that began in 2013. Despite a growing number of ZIKV studies in the past three years, many aspects of the virus remain poorly characterized, particularly the spectrum of species involved in its transmission cycles. Here, we review the mosquito and vertebrate host species potentially involved in ZIKV vector-borne transmission worldwide. We also provide an evidence-supported analysis regarding the possibility of ZIKV spillback from an urban cycle to a zoonotic cycle outside Africa, and we review hypotheses regarding recent emergence and evolution of ZIKV. Finally, we identify critical remaining gaps in the current knowledge of ZIKV vector-borne transmission.

Indexed as

AnimalsCulicidaeEvolution, MolecularHumansMosquito VectorsZika VirusZika Virus Infection

Identifiers

PMID30886369
PMCPMC8900209
OpenAlexW2920949367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.