Evidence map›Paper›PMID 30886321›Full record

ArticleEuropean journal of clinical nutrition2019

Body composition and nutritional status in malignant pleural mesothelioma: implications for activity levels and quality of life.

Emily Jeffery, Y C Gary Lee, Robert U Newton, Philippa Lyons-Wall, Joanne McVeigh, Anna K Nowak, Hui Min Cheah, Bella Nguyen, Deirdre B Fitzgerald, Jenette Creaney and 2 more

Registry-linked trialOpen access · greenAbstract read
PubMed Publisher
In one paragraph

Article in European journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06491784 (EXercise TheRApy in Mesothelioma - A Feasibility Study), which is not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06491784 naunknown statusnot on this mapstarted 2024, after this paper: background citation

EXercise TheRApy in Mesothelioma - A Feasibility Study

TypeinterventionalSponsorNHS Greater Glasgow and ClydeRan2024 to 2025Enrolled40ConditionsMesotheliomaArmsExercise Therapy
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Trial
  2. Pleural mesothelioma.Nature reviews. Disease primers · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Malignant pleural disease.Breathe (Sheffield, England) · 2023
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Emily JefferyExercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.ORCID http://orcid.org/0000-0002-9463-3196
Y C Gary LeeRespiratory Department, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.
Robert U NewtonExercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.ORCID http://orcid.org/0000-0003-0302-6129
Philippa Lyons-WallSchool of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
Joanne McVeighSchool of Occupational Therapy, Speech Therapy and Social Work, Curtin University, Perth, WA, Australia.
Anna K NowakMedical School, University of Western Australia, Crawley, WA, Australia.
Hui Min CheahMedical School, University of Western Australia, Crawley, WA, Australia.
Bella NguyenMedical Oncology Department, Sir Charles Gairdner Hospital, Nedlands, WA, Australia.
Deirdre B FitzgeraldRespiratory Department, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.
Jenette CreaneyInstitute for Respiratory Health, Nedlands, WA, 6009, Australia.
Leon StrakerSchool of Physiotherapy and Exercise Science, Curtin University, Perth, WA, Australia.
Carolyn J Peddle-McIntyreExercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia. c.mcintyre@ecu.edu.au.
Edith Cowan University · AUThe University of Western Australia · AUSir Charles Gairdner Hospital · AUCurtin University · AUUniversity of the Witwatersrand · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesMalignant pleural mesothelioma (MPM) is an incurable cancer and optimizing daily physical activity and quality of life are key goals of patient management. Little is known about the prevalence of pre-sarcopenia and malnutrition in MPM or their associations with patient outcomes. This study aimed to determine the prevalence of pre-sarcopenia and malnutrition in MPM and investigate if activity levels and quality of life differed according to body composition and nutritional status. SUBJECTS/

methodsPatients with a diagnosis of MPM were recruited. Pre-sarcopenia was defined as low appendicular skeletal muscle mass (≤ 7.26 kg/m

resultsSixty-one people participated (79% male, median age 69 [IQR 62-74] years and median BMI 25.8 [IQR 24.3-28.4] kg/m

conclusionParticipants with MPM had high rates of pre-sarcopenia and malnutrition. Pre-sarcopenia was associated with poorer activity levels, whilst malnutrition was associated with poorer quality of life. Interventions that aim to address reduced muscle mass and weight loss, should be tested in MPM to assess their impact on patient outcomes.

Indexed as

Body CompositionNutritional StatusQuality of LifeAgedAustraliaCross-Sectional StudiesDietExerciseFemaleHumansLung NeoplasmsMaleMalnutritionMesotheliomaMesothelioma, MalignantMiddle Aged

Identifiers

PMID30886321
OpenAlexW2922456708

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.