Evidence map›Paper›PMID 30886216›Full record

ArticleScientific reports2019

A substitute variety for agronomically and medicinally important Serenoa repens (saw palmetto).

Yogini Jaiswal, Daniel Weber, Aaron Yerke, Yanling Xue, Danielle Lehman, Taufika Williams, Tiqiao Xiao, Daniel Haddad, Leonard Williams

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yogini JaiswalCenter for Excellence in Post Harvest Technologies, North Carolina Agricultural and Technical State University, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC, 28081, USA. yoginijaiswal@gmail.com.
Daniel WeberFraunhofer Development Centre X-ray Technology EZRT, a Division of Fraunhofer Institute for Integrated Circuits IIS, Department Magnetic Resonance and X-ray Imaging MRB, Am Hubland D-97074, Wuerzburg, Germany.
Aaron YerkeDepartment of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, North Carolina, 28223, USA.
Yanling XueShanghai Advanced Research Institute, Chinese Academy of Sciences, Pudong District, Shanghai, 201203, P. R. China.
Danielle LehmanMass Spectrometry Facility, Department of Chemistry, North Carolina State University 2620 Yarbrough Drive, Campus Box 8204, Raleigh, NC, 27695, USA.
Taufika WilliamsMass Spectrometry Facility, Department of Chemistry, North Carolina State University 2620 Yarbrough Drive, Campus Box 8204, Raleigh, NC, 27695, USA.
Tiqiao XiaoShanghai Advanced Research Institute, Chinese Academy of Sciences, Pudong District, Shanghai, 201203, P. R. China.
Daniel HaddadFraunhofer Development Centre X-ray Technology EZRT, a Division of Fraunhofer Institute for Integrated Circuits IIS, Department Magnetic Resonance and X-ray Imaging MRB, Am Hubland D-97074, Wuerzburg, Germany.
Leonard WilliamsCenter for Excellence in Post Harvest Technologies, North Carolina Agricultural and Technical State University, The North Carolina Research Campus, 500 Laureate Way, Kannapolis, NC, 28081, USA. llw@ncat.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serenoa repens (saw palmetto) berries are one of the most consumed medicinal herbs in the United States and the wild green variety is used in the initial therapy of benign prostatic hyperplasia (BPH), globally. Use of saw palmetto is approved by the German Commission E, and several clinical trials are underway for evaluation of its efficacy. Exploitation of its habitats and over foraging imperil this plant, which only grows in the wild. This is the first study, to propose the use of the S. repens forma glauca (silver variety) as a qualitative substitute for the wild variety, to support its conservation. We compared tissue microstructures and lipid and water distribution through spatial imaging and examined metabolite distribution of three tissue domains and whole berries. This combined approach of 3D imaging and metabolomics provides a new strategy for studying phenotypic traits and metabolite synthesis of closely related plant varieties.

Indexed as

Conservation of Natural ResourcesFruitHumansLipid MetabolismLipidsMaleMetabolomicsPhytotherapyPlant ExtractsPlants, MedicinalProstatic HyperplasiaSecondary MetabolismSerenoaSpatial AnalysisWaterLipidsPlant Extractssaw palmetto extractWater

Identifiers

PMID30886216
PMCPMC6423146

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.