Evidence map›Paper›PMID 30886064›Full record

ReviewBioscience reports2019

The function of histone acetylation in cervical cancer development.

Shanshan Liu, Weiqin Chang, Yuemei Jin, Chunyang Feng, Shuying Wu, Jiaxing He, Tianmin Xu

Open access · goldAbstract readReview
In one paragraph

Review in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. LncRNA-Histone Modification Crosstalk: Orchestrating Cancer Pathobiology.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
  6. Epigenetic regulation in gynecological cancers: a paradigm shift in immunotherapy strategies.Journal of experimental & clinical cancer research : CR · 2025
    Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Shanshan LiuDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.ORCID 0000-0002-6421-2585
Weiqin ChangSurgical Department, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.
Yuemei JinDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.
Chunyang FengDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.
Shuying WuDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.
Jiaxing HeDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China.
Tianmin XuDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, 218 Ziqiang Road, Jilin 130041, P.R. China xutianmin@126.com.ORCID 0000-0002-1219-061X
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer is the fourth most common female cancer in the world. It is well known that cervical cancer is closely related to high-risk human papillomavirus (HPV) infection. However, epigenetics has increasingly been recognized for its role in tumorigenesis. Epigenetics refers to changes in gene expression levels based on non-gene sequence changes, primarily through transcription or translation of genes regulation, thus affecting its function and characteristics. Typical post-translational modifications (PTMs) include acetylation, propionylation, butyrylation, malonylation and succinylation, among which the acetylation modification of lysine sites has been studied more clearly so far. The acetylation modification of lysine residues in proteins is involved in many aspects of cellular life activities, including carbon metabolism, transcriptional regulation, amino acid metabolism and so on. In this review, we summarize the latest discoveries on cervical cancer development arising from the aspect of acetylation, especially histone acetylation.

Indexed as

AcetylationAnimalsFemaleHistone AcetyltransferasesHistone DeacetylasesHistonesHumansProtein Processing, Post-TranslationalUterine Cervical NeoplasmsHistone AcetyltransferasesHistone DeacetylasesHistonesCervical cancerEpigeneticsHistone acetylation

Identifiers

PMID30886064
PMCPMC6465204
OpenAlexW2921481615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.