Evidence map›Paper›PMID 30886062›Full record

ArticleBioscience reports2019

MIR100HG: a credible prognostic biomarker and an oncogenic lncRNA in gastric cancer.

Jun Li, Qingfeng Xu, Wen Wang, Shaojun Sun

Open access · goldAbstract read
In one paragraph

Article in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
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  6. A concise review on the role of MIR100HG in human disorders.Journal of cellular and molecular medicine · 2023
    Review
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  13. Review
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  18. Downregulation of MIR100HG Induces Apoptosis in Human Megakaryoblastic Leukemia Cells.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2021
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Jun LiDepartment of Clinical Laboratory, Jining NO. 1 People's Hospital; Affiliated Jining NO. 1 People's Hospital of Jining Medical University, Jining Medical University, Jining 272011, Shandong, China.
Qingfeng XuDepartment of Hematology-Oncology, People's Hospital of Gaotang County Affiliated to Jining Medical University, Liaocheng 252800, Shandong, China.
Wen WangDepartment of Clinical Laboratory, People's Hospital of Binzhou City, Binzhou 256600, Shandong, China.
Shaojun SunDepartment of Clinical Laboratory, Brain Hospital of Liaocheng City, People's Hospital of Liaocheng City, Liaocheng 252000, Shandong, China sunshaojunlc@126.com.ORCID 0000-0003-2088-1565
Liaocheng People's Hospital · CNBinzhou People's Hospital · CNHuaian First People’s Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The MIR100HG expression was observed to be up-regulated or down-regulated in human cancer tissues depending on tumor types. However, there was no report about the role of MIR100HG in gastric cancer. In our study, we first found levels of MIR100HG expression were increased in gastric cancer cell lines and tissue samples compared with normal gastric epithelial cell line and adjacent normal gastric mucosa tissue samples, respectively. Moreover, high MIR100HG expression was positively associated with clinical stage, tumor invasion, lymph node metastasis, and distant metastasis in gastric cancer patients. Survival analysis showed MIR100HG expression was negative correlated with clinical outcome in gastric cancer patients from The Cancer Genome Atlas (TCGA) database or our study, and high MIR100HG expression served as an independent poor prognostic factor for gastric cancer patient's overall survival. The study

Indexed as

Biomarkers, TumorCell MovementCell ProliferationFemaleHumansMaleMicroRNAsMiddle AgedNeoplasm InvasivenessPrognosisRNA, Long NoncodingStomach NeoplasmsSurvival AnalysisBiomarkers, TumorMicroRNAsMIRN100 microRNA, humanRNA, Long Noncodingbiomarkersgastric cancerlarge intervening non-coding RNAMIR100HG

Identifiers

PMID30886062
PMCPMC6449568
OpenAlexW2921693476

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.