ArticleThe Annals of thoracic surgery2019
Repair of Total Anomalous Pulmonary Venous Connection: Risk Factors for Postoperative Obstruction.
Article in The Annals of thoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Multimodality Imaging in Presurgical Evaluation of Total Anomalous Pulmonary Venous Connection: Single-Center Practice Variability and a Systematic Review of Diagnostic Error.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2025Pooled it
- Risk factors for postoperative pulmonary venous obstruction after surgical repair of total anomalous pulmonary venous connection: a systemic review and meta-analysis.Interactive cardiovascular and thoracic surgery · 2022Pooled it
- Sutureless Closure Versus Conventional Technique in the Primary Surgery of Total Anomalous Pulmonary Venous Connection: A Systematic Review and Meta-analysis.Pediatric cardiology · 2022Pooled it
- An Unusual Cause of Common Chamber to LA Anastomosis Obstruction in Supracardiac TAPVC.Annals of cardiac anaesthesia · 2026Article
- Exercise Capacity and Pulmonary Function in Pediatric Patients With Anomalous Pulmonary Venous Connection Post-Surgical Repair: A Retrospective Analysis.The Kaohsiung journal of medical sciences · 2026Article
- Comparison of the Efficacy and Safety of Sutureless Technique Versus Conventional Surgery in the Initial Treatment of Total Anomalous Pulmonary Venous Connection: A Systematic Review and Meta-Analysis.Pulmonary circulation · 2026Review
- Predictive Factors for Prolonged Ventilatory Support in Infants Undergoing Total Anomalous Pulmonary Venous Connection Repair: A Retrospective Cohort Study.Reviews in cardiovascular medicine · 2025Article
- Predicting the Need for Pulmonary Venous Reintervention in Total Anomalous Pulmonary Venous Connection: The Role of Preoperative Echocardiographic Metrics.Echocardiography (Mount Kisco, N.Y.) · 2025Article
- Valsartan to Prevent Acquired Pulmonary Vein Stenosis in Pediatric Patients After Total Anomalous Pulmonary Venous Connection Surgery.Journal of the American Heart Association · 2025Article
- Quantification of 3-Dimensional Confluence-Atrial Morphology in Supracardiac Total Anomalous Pulmonary Venous Connection.JACC. Asia · 2024Article
- Insight into the research history and trends of total anomalous pulmonary venous connection: a bibliometric analysis.Journal of cardiothoracic surgery · 2024Article
- Assessing the risk of reoperation for mild pulmonary vein obstruction post-TAPVC repair: a retrospective cohort study.Frontiers in cardiovascular medicine · 2024Article
- Unobstructed infracardiac total anomalous pulmonary venous connection in a 7-month-old infant: A rare case report.Clinical case reports · 2023Article
- Assessment of left atrial deformation in patients with total anomalous pulmonary venous connection by two-dimensional speckle-tracking echocardiography.Heart and vessels · 2023Article
- A clinical case of successful palliative endovascular treatment of a patient with a single ventricle, mitral valve atresia, an intact atrial septum and persistent cardinal vein.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2023Article
- [Integrated management during the perinatal period for total anomalous pulmonary venous connection].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023Article
- Total Anomalous Pulmonary Venous Connection: Surgical Outcomes and Risk Factors for Postoperative Pulmonary Vein Obstruction.Acta Cardiologica Sinica · 2023Article
- Outcomes of total anomalous pulmonary venous drainage repair in neonates and the impact of pulmonary hypertension on survival.JTCVS open · 2022Article
- Fetal Doppler Echocardiographic Assessment Predicts Severe Postnatal Obstruction in Total Anomalous Pulmonary Venous Connection.Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography · 2022Article
- Strategy of delayed repair of total anomalous pulmonary venous connection in right atrial isomerism and functional single ventricle.JTCVS open · 2022Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundPulmonary venous obstruction after repair of total anomalous pulmonary venous connection (TAPVC) results in substantial morbidity and mortality. Risk factors for postoperative obstruction remain ambiguous. In addition, the existing literature has no standard definition for preoperative obstruction, making patient counseling difficult.
methodsAll patients undergoing repair of TAPVC at our institution from January 1, 2006, to October 23, 2017, were identified. The primary outcome was the development of postoperative obstruction, analyzed as a time-to-event outcome. Clinical information was extracted to assess risk factors. Degrees of preoperative obstruction were defined based on echocardiographic, catheterization, and clinical findings. Univariable and multivariable Cox proportional hazard regression methods were used to identify factors associated with the primary outcome.
resultsDuring the study interval, 119 patients underwent repair of TAPVC (40% single ventricle), and postoperative obstruction developed in 25 patients (21%). Risk factors associated with obstruction were heterotaxy syndrome, single-ventricle heart disease, additional procedures at the time of vein repair, mixed-type TAPVC, and preoperative obstruction. Having even mild preoperative obstruction (≥1.2 m/s by Doppler echocardiography) was predictive of postoperative obstruction. A multivariable model showed mixed-type TAPVC and the presence of preoperative obstruction were associated with a more than twofold greater hazard of obstruction.
conclusionsTAPVC in the setting of heterotaxy and a single ventricle remains challenging, with high rates of postoperative obstruction. Mixed-type TAPVC is an independent risk factor for postoperative obstruction, particularly in patients with isolated TAPVC. Even mild preoperative obstruction is a risk factor for postoperative obstruction. These results may help risk-stratify TAPVC patients.
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