Evidence map›Paper›PMID 30885661›Full record

ArticleJournal of pharmaceutical sciences2019

Spectrometric Smartphone-Based System for Ibuprofen Quantification in Commercial Dosage Tablets.

Miguel Ángel Aguirre, Kenneth D Long, Brian T Cunningham

Open access · greenAbstract read
In one paragraph

Article in Journal of pharmaceutical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Miguel Ángel AguirreDepartment of Analytical Chemistry and Food Science and University Institute of Materials, Faculty of Science, University of Alicante, P.O. Box 99, 03080 Alicante, Spain. Electronic address: aguirre.pastor@ua.es.
Kenneth D LongDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; University of Illinois College of Medicine at Urbana-Champaign, Urbana, Illinois 61801.
Brian T CunninghamDepartment of Bioengineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; Department of Electrical and Computer Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801. Electronic address: bcumming@illinois.edu.
University of Illinois Urbana-Champaign · USUniversity of Alicante · ES

Funding

Photonic Crystal Based Point-of-Care Detection of HIV Viral Load Using a Smartphone BiosensorF30AI122925 · NIAID · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI LONG, KENNETH · 2016 to 2019
$159k
NIAID NIH HHS F30 AI122925
6 · The paper itself

Abstract

A rapid and portable analytical methodology has been developed for ibuprofen (IBU) quantification in commercial dosage tablets using a spectrometric smartphone-based system. The analytical methodology employs point-of-use approaches both for sample preparation and detection, demonstrating its potential utility for portable quality control of pharmaceutical products. In this work, IBU is dissolved in methanol and then treated with a Co(II) aqueous solution, forming a blue complex which is extractable by dispersive liquid-liquid microextraction. Then, the sample's absorption spectrum is directly measured by a spectrometric smartphone-based system using cartridge made of polyoxymethylene for solvent compatibility. The main experimental factors affecting the dispersive liquid-liquid microextraction of Co-IBU complex were optimized using a multivariate analysis. Under optimized conditions, a working range between 20 and 80 μg mL

Indexed as

Analgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalIbuprofenLiquid Phase MicroextractionSmartphoneSpectrophotometryTabletsAnalgesics, Non-NarcoticAnti-Inflammatory Agents, Non-SteroidalIbuprofenTabletsabsorption spectroscopyactive pharmaceutical ingredientanalysisanalytical chemistryAPIdispersive liquid-liquid microextractionDLLMEIBUibuprofenimage analysislimit of quantificationLOQregulatory sciencetransmission, reflection, intensityTRI

Identifiers

PMID30885661
PMCPMC6640107
OpenAlexW2921907490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.