Evidence map›Paper›PMID 30885539›Full record

ArticleTrends in immunology2019

To Sleep, Perchance to Survive?

Richard M Ransohoff

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Richard M RansohoffThird Rock Ventures, 29 Newbury Street, Boston, MA 02116, USA; Department of Cell Biology, Harvard Medical School, 240 Longwood Avenue Boston, MA 02115, USA. Electronic address: rransohoff@thirdrockventures.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multicellular organisms exist in a sea of microbes. Survival is enabled by an immense diversity of antimicrobial peptides (AMPs) that maintain homeostasis with the microbiota. During pathogen infection, fruit fly survival varies directly with sleep. A newly-identified fruit fly sleep-regulator is also an AMP (Toda et al. Science 2019;363:509-515). Its characterization may clarify the association between sleep and surviving infection.

Indexed as

Antimicrobial Cationic PeptidesMicrobiotaAnimalsDrosophilaAntimicrobial Cationic Peptides

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.