ArticleAmerican journal of surgery2019
Risk factors for infection and evaluation of Sepsis-3 in patients with trauma.
Article in American journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04438187 (Trial of Antimicrobial Restraint in Presumed Pneumonia), which is not on this map. Cited by 16 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Trial of Antimicrobial Restraint in Presumed Pneumonia
Who cites it
16 citing papers in PubMed.
- Glycemic variability improves risk prediction and reveals a mortality threshold in orthopedic trauma patients with sepsis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2026Article
- Adjudication instrument for infection in critically injured trauma patients.Trauma surgery & acute care open · 2026Article
- Fragment end motif analysis to distinguish pathogens from contaminants in enriched plasma microbial DNA.medRxiv : the preprint server for health sciences · 2025Article
- Enrichment of Microbial DNA in Plasma to Improve Pathogen Detection in Sepsis: A Pilot Study.Clinical chemistry · 2025Article
- Identifying early predictive and diagnostic biomarkers and exploring metabolic pathways for sepsis after trauma based on an untargeted metabolomics approach.Scientific reports · 2025Article
- Epidemiology, Risk Factors, and Predictive Modelling of Post-Traumatic Sepsis: A Retrospective Cohort Study.Risk management and healthcare policy · 2025Article
- Organ Donation after Open Abdominal Management with Negative-Pressure Dressing: A Case Report.Surgical case reports · 2025Article
- The Relationship Between Acute Kidney Injury in Sepsis Patients and Coagulation Dysfunction and Prognosis.Open access emergency medicine : OAEM · 2024Article
- Predictors of sepsis in trauma patients: a National Trauma Data Bank analysis.Frontiers in medicine · 2024Article
- Defining Posttraumatic Sepsis for Population-Level Research.JAMA network open · 2023Article
- Clinical Impact of Colonization with Carbapenem-Resistant Gram-Negative Bacteria in Critically Ill Patients Admitted for Severe Trauma.Pathogens (Basel, Switzerland) · 2022Article
- Extensive rib resection followed by thoracic wall reconstruction using polytetrafluoroethylene mesh and titanium plates for refractory intercostal artery bleeding induced by severe blunt thoracic injury: report of a case.Fujita medical journal · 2022Article
- The impact of infection complications after trauma differs according to trauma severity.Scientific reports · 2021Article
- SOFA score is superior to APACHE-II score in predicting the prognosis of critically ill patients with acute kidney injury undergoing continuous renal replacement therapy.Renal failure · 2020Article
- Trends, Cost, and Mortality From Sepsis After Trauma in the United States: An Evaluation of the National Inpatient Sample of Hospitalizations, 2012-2016.Critical care medicine · 2020Article
- Preparation and in Vitro Property Research of Cholic Acid Nanoparticles with Dual-functions of Hemostasis and Antibacterial.Iranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundWe aim to examine the risk factors associated with infection in trauma patients and the Sepsis-3 definition.
methodsThis was a retrospective cohort study of adult trauma patients admitted to a Level I trauma center between January 2014 and January 2016.
resultsA total of 1499 trauma patients met inclusion criteria and 15% (n = 232) had an infection. Only 19.8% (n = 46) of infected patients met criteria for Sepsis-3, with the majority (43%) of infected cases having a Sequential Organ Failure Assessment (SOFA) score greater on admission compared to the time of suspected infection. In-hospital death was 7% vs 9% (p = 0.65) between Sepsis-3 and infected patients, respectively. Risk factors associated with infection were female sex, admission SOFA score, Elixhauser score, and severe injury (P < 0.05).
conclusionPatients with trauma often arrive with organ dysfunction, which adds complexity and inaccuracy to the operational definition of Sepsis-3 using changes in SOFA scores. Injury severity score, comorbidities, SOFA score, and sex are risk factors associated with developing an infection after trauma.
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