ReviewBiomedical engineering online2019
Processing of collagen based biomaterials and the resulting materials properties.
Review in Biomedical engineering online, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 200 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
200 citing papers in PubMed, 3 syntheses or guidelines pooled it, 503 citations in OpenAlex.
- Fish collagen for skin wound healing: a systematic review in experimental animal studies.Cell and tissue research · 2022Pooled it
- Collagen from Marine Sources and Skin Wound Healing in Animal Experimental Studies: a Systematic Review.Marine biotechnology (New York, N.Y.) · 2021Pooled it
- Live long and active: Polypeptide-mediated assembly of antibody variable fragments.Advanced drug delivery reviews · 2020Pooled it
- Prefabricated CAD/CAM zirconia membrane versus contour augmentation with early implant placement in the anterior maxilla: a randomized controlled clinical trial.International journal of implant dentistry · 2026Trial
- Advanced fabrication protocol of an elastic porous membrane for organ-on-a-chip applications.SLAS technology · 2026Article
- Membrane composition modulates podocyte-renal endothelial cell interactions in a humanized glomerular basement membrane-on-a-chip.Scientific reports · 2026Article
- Assessment of Bovine Collagen Manufactured via Cellular Agriculture.ACS biomaterials science & engineering · 2026Article
- Evaluation of angiogenic, osteogenic, and antimicrobial potential of novel type X collagen-derived GBR membrane: an in vivo preliminary study.Odontology · 2026Article
- Silk Fibroin for Biomedical Applications with Emphasis on Bioimaging, Biosensing and Regenerative Systems: A Review.Molecules (Basel, Switzerland) · 2026Review
- Seeing through collagen: integrative pro-regenerative corneal implants for clearer future.NPJ Regenerative medicine · 2026Review
- RNA-Seq of Gingival Fibroblasts Grown on Collagen Membranes and Hyaluronic Acid.Journal of functional biomaterials · 2026Article
- Article
- Mesoporous bioactive glass-recombinant collagen III nanocomposite capsule promotes skin wound healing via adaptive immune modulation.Regenerative biomaterials · 2026Article
- Valorisation of fish scales and bones: a sustainable source of bioactive proteins and collagen for nutraceuticals.Bioresources and bioprocessing · 2025Review
- Effects of a Drying Treatment on the Mechanical Properties and Hemodynamic Characteristics of Bovine Pericardial Bioprosthetic Valves.Journal of functional biomaterials · 2025Article
- Native Collagen and Total Lipid Extract Obtained fromMarine drugs · 2025Article
- Current Insights and Future Directions in Scar Management and Skin Regeneration.International journal of molecular sciences · 2025Review
- Article
- Assessing the Potential of Caprine Collagen Type I in the Development of Medical Devices.Biomacromolecules · 2025Article
- Photo-Cross-Linked Porous Hybrid Networks Based on Insoluble Collagen and Poly(trimethylene carbonate).Biomacromolecules · 2025Article
140 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Collagen, the most abundant extracellular matrix protein in animal kingdom belongs to a family of fibrous proteins, which transfer load in tissues and which provide a highly biocompatible environment for cells. This high biocompatibility makes collagen a perfect biomaterial for implantable medical products and scaffolds for in vitro testing systems. To manufacture collagen based solutions, porous sponges, membranes and threads for surgical and dental purposes or cell culture matrices, collagen rich tissues as skin and tendon of mammals are intensively processed by physical and chemical means. Other tissues such as pericardium and intestine are more gently decellularized while maintaining their complex collagenous architectures. Tissue processing technologies are organized as a series of steps, which are combined in different ways to manufacture structurally versatile materials with varying properties in strength, stability against temperature and enzymatic degradation and cellular response. Complex structures are achieved by combined technologies. Different drying techniques are performed with sterilisation steps and the preparation of porous structures simultaneously. Chemical crosslinking is combined with casting steps as spinning, moulding or additive manufacturing techniques. Important progress is expected by using collagen based bio-inks, which can be formed into 3D structures and combined with live cells. This review will give an overview of the technological principles of processing collagen rich tissues down to collagen hydrolysates and the methods to rebuild differently shaped products. The effects of the processing steps on the final materials properties are discussed especially with regard to the thermal and the physical properties and the susceptibility to enzymatic degradation. These properties are key features for biological and clinical application, handling and metabolization.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.