ArticleBMC musculoskeletal disorders2019
Efficacy of platelet-rich plasma in arthroscopic repair for discoid lateral meniscus tears.
Article in BMC musculoskeletal disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- No evidence in support of arthroscopic partial meniscectomy in adults with degenerative and nonobstructive meniscal symptoms: a level I evidence-based systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Platelet-rich plasma use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies.Journal of orthopaedic surgery and research · 2022Pooled it
- Biological augmentation of meniscal repair: a systematic review.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Platelet-rich plasma (PRP) augmentation does not result in more favourable outcomes in arthroscopic meniscal repair: a meta-analysis.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2022Pooled it
- Clinical efficacy of platelet-rich plasma as adjuvant therapy in patients undergoing arthroscopic repair of meniscal injury.The Journal of international medical research · 2020Pooled it
- Systematic reviews in PRP-augmented meniscal repair have limited methodological quality: A systematic overview.Journal of experimental orthopaedics · 2026Article
- Rethinking meniscal repair in patients over 40: Extending the boundaries of joint preservation.World journal of methodology · 2026Review
- A clinical practice review: augmentation of meniscoligamentous structures for primary prevention of knee joint deterioration.Annals of joint · 2026Review
- Surgical Management of the Discoid Lateral Meniscus: a Systematic Review of Outcomes.Current reviews in musculoskeletal medicine · 2025Review
- Efficacy and Safety of Platelet-Rich Plasma for Patients With Meniscal Injury: A Systematic Review and Meta-analysis of Randomized Controlled Trials.Orthopaedic journal of sports medicine · 2025Review
- How to Improve Meniscal Repair through Biological Augmentation: A Narrative Review.Journal of clinical medicine · 2024Review
- Biologic Augmentation of Isolated Meniscal Repair.Current reviews in musculoskeletal medicine · 2024Review
- Discoid meniscus: Treatment considerations and updates.World journal of orthopedics · 2024Review
- Utility of Platelet-Rich Plasma Therapy in the Management of Meniscus Injuries: A narrative review.Orthopedic reviews · 2024Article
- The Current Role of Biologics for Meniscus Injury and Treatment.Current reviews in musculoskeletal medicine · 2022Review
- Clinical and Functional Outcome of Meniscal Injuries Treated with Platelet-Rich Plasma: A Single-Center Case Series.International journal of environmental research and public health · 2022Article
- Applications and prospects of different functional hydrogels in meniscus repair.Frontiers in bioengineering and biotechnology · 2022Review
- Meniscus treatment: biological augmentation strategies: a narrative review.Annals of joint · 2022Review
- A review of strategies for development of tissue engineered meniscal implants.Biomaterials and biosystems · 2021Review
- The use of autologous platelet-rich fibrin matrix combined with meniscal repair in the treatment of parameniscal cyst: clinical results and cyst recurrence after 2-year of follow up.Journal of experimental orthopaedics · 2021Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundTo evaluate the clinical results of arthroscopic repair with or without platelet-rich plasma (PRP) for tears of the discoid lateral meniscus (DLM).
methodsTwenty-nine patients with DLM tears within a stable knee were arthroscopically treated with meniscal suture repair. Of those, 14 were augmented with platelet-rich plasma (PRP), and 15 were performed without PRP augmentation. Patients were evaluated at baseline (the day before surgery) and then 12 and 24 months after the last injection. Evaluation included the Lysholm score, and Ikeuchi grade, Visual analogue score (VAS) for pain and failure rate. Failure was defined by patients developing symptoms of joint line pain, locking, swelling or requiring repeat arthroscopy.
resultsThere was no difference in the failure rate in the PRP group (1 of 14) compared with the non-PRP group (2 of 15) (P = 0.58). Statistically significant improvement in Lysholm score, Ikeuchi grade and VAS for pain was documented at the last follow-up compared with baseline in both PRP and non-PRP group. No significantly difference was found between the PRP group and non-PRP group on Lysholm score, Ikeuchi grade and VAS for pain at the last follow-up. In the univariate analysis of each variable, younger age (P = 0.036) and longer follow-up duration (P = 0.043) were statistically associated with a better function improvement. Whereas in multivariate analysis, only younger age (P = 0.004) was significantly associated with a better function improvement.
conclusionWith regard to clinical evaluations in arthroscopic repair for DLM tears, PRP group had similar effect in pain relief and functional improvement to non-PRP group at mid-term follow-up. Future larger prospective studies with a longer follow-up are needed to determine whether PRP should be used with DLM repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.