SynthesisBMC cardiovascular disorders2019
Associations between ADIPOQ polymorphisms and coronary artery disease: a meta-analysis.
Synthesis in BMC cardiovascular disorders, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 16 citations in OpenAlex.
- The Association Between Adiponectin Gene Polymorphism (rs1501299) and Metabolic Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Genetic Insights Into Type 2 Diabetes Mellitus Susceptibility: A Case-Control Study of theGenetics research · 2025Article
- Chronic Kidney Disease: Interaction of Adiponectin Gene Polymorphisms and Diabetes.International journal of molecular sciences · 2023Article
- Polymorphism in Adiponectin and Adiponectin Receptor Genes in Diabetes Mellitus Pathogenesis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2022Article
- Stage specific transcriptome profiles at cardiac lineage commitment during cardiomyocyte differentiation from mouse and human pluripotent stem cells.BMB reports · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether adiponectin (ADIPOQ) polymorphisms are associated with coronary artery disease (CAD) remain controversial. Therefore, we performed this meta-analysis to better explore potential roles of ADIPOQ polymorphisms in CAD.
methodsPubMed, Web of Science, Embase and CNKI were searched for eligible studies. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated.
resultsTotally 45 studies were included for pooled analyses. A significant association with the susceptibility to CAD was detected for rs2241766 (dominant model: p = 0.0009, OR = 0.82, 95%CI 0.73-0.92; recessive model: p = 0.04, OR = 1.29, 95%CI 1.02-1.64; allele model: p < 0.0001, OR = 0.80, 95%CI 0.73-0.88) polymorphism in overall population. Further subgroup analyses by ethnicity showed that rs1501299 polymorphism was significantly associated with the susceptibility to CAD in East Asians, whereas rs2241766 polymorphism was significantly associated with the susceptibility to CAD in Caucasians, East Asians and South Asians.
conclusionsOur findings indicated that rs1501299 and rs2241766 polymorphisms both affect the susceptibility to CAD in certain populations.
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