Evidence map›Paper›PMID 30884946›Full record

ArticleAnalytical chemistry2019

Online Measurement of Glucose Consumption from HepG2 Cells Using an Integrated Bioreactor and Enzymatic Assay.

Anna G Adams, Radha Krishna Murthy Bulusu, Nikita Mukhitov, Jose L Mendoza-Cortes, Michael G Roper

Abstract read
In one paragraph

Article in Analytical chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  6. Article
  7. A frugal microfluidic pump.Lab on a chip · 2021
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna G AdamsDepartment of Chemistry and Biochemistry , Florida State University , 95 Chieftain Way , Tallahassee , Florida 32306 , United States.
Radha Krishna Murthy BulusuDepartment of Chemical and Biomedical Engineering , FAMU-FSU College of Engineering , 2525 Pottsdamer Street , Tallahassee , Florida 32310 , United States.
Nikita MukhitovDepartment of Chemistry and Biochemistry , Florida State University , 95 Chieftain Way , Tallahassee , Florida 32306 , United States.
Jose L Mendoza-CortesDepartment of Chemical and Biomedical Engineering , FAMU-FSU College of Engineering , 2525 Pottsdamer Street , Tallahassee , Florida 32310 , United States.
Michael G RoperDepartment of Chemistry and Biochemistry , Florida State University , 95 Chieftain Way , Tallahassee , Florida 32306 , United States.ORCID 0000-0002-0184-1333

Funding

Microfluidic Devices to Determine Roles of Islet-Secreted LeptinR01DK080714 · NIDDK · FLORIDA STATE UNIVERSITY · PI ROPER, MICHAEL GABRIEL · 2008 to 2025
$5.5M
NIDDK NIH HHS R01 DK080714
6 · The paper itself

Abstract

Hepatocytes help to maintain glucose homeostasis in response to a variety of signals, including pancreatic hormones such as insulin. Insulin is released from the pancreas with variable dynamics, yet the role that these play in regulating glucose metabolism in the liver is still unclear. In this study, a modular microfluidic system was developed to quantitatively measure the effect of insulin dynamics on glucose consumption by a human hepatocarcinoma cell line, HepG2. A microfluidic bioreactor that contained 10

Indexed as

BioreactorsEnzyme AssaysGlucoseMicrofluidic Analytical TechniquesGlucose OxidaseHep G2 CellsHorseradish PeroxidaseHumansParticle SizeSurface PropertiesTumor Cells, CulturedGlucoseGlucose OxidaseHorseradish Peroxidase

Identifiers

PMID30884946
PMCPMC6472493

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.