Evidence map›Paper›PMID 30884846›Full record

ArticleInternational journal of molecular sciences2019

Distribution of Gadolinium in Rat Heart Studied by Fast Field Cycling Relaxometry and Imaging SIMS.

Claudia Bonechi, Marco Consumi, Marco Matteucci, Gabriella Tamasi, Alessandro Donati, Gemma Leone, Luca Menichetti, Claudia Kusmic, Claudio Rossi, Agnese Magnani

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Claudia BonechiDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. claudia.bonechi@unisi.it.ORCID 0000-0002-4328-3253
Marco ConsumiDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. marco.consumi@unisi.it.
Marco MatteucciCNR Institute of Clinical Physiology, Area di Ricerca "S. Cataldo", Via Giuseppe Moruzzi 1, 56124 Pisa, Italy. matteucci@ifc.cnr.it.
Gabriella TamasiDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. gabriella.tamasi@unisi.it.ORCID 0000-0002-6796-8863
Alessandro DonatiDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. alessandro.donati@unisi.it.
Gemma LeoneDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. gemma.leone@unisi.it.
Luca MenichettiCNR Institute of Clinical Physiology, Area di Ricerca "S. Cataldo", Via Giuseppe Moruzzi 1, 56124 Pisa, Italy. luca.menichetti@ifc.cnr.it.
Claudia KusmicCNR Institute of Clinical Physiology, Area di Ricerca "S. Cataldo", Via Giuseppe Moruzzi 1, 56124 Pisa, Italy. kusmic@ifc.cnr.it.
Claudio RossiDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. claudio.rossi@unisi.it.
Agnese MagnaniDepartment of Biotechnology, Chemistry and Pharmacy, Via Aldo Moro 2, 53100 Siena, Italy. agnese.magnani@unisi.it.
Consorzio Interuniversitario per lo Sviluppo dei Sistemi a Grande Interfase · ITIstituto di Fisiologia Clinica · ITNational Interuniversity Consortium of Materials Science and Technology · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research on microcirculatory alterations in human heart disease is essential to understand the genesis of myocardial contractile dysfunction and its evolution towards heart failure. The use of contrast agents in magnetic resonance imaging is an important tool in medical diagnostics related to this dysfunction. Contrast agents significantly improve the imaging by enhancing the nuclear magnetic relaxation rates of water protons in the tissues where they are distributed. Gadolinium complexes are widely employed in clinical practice due to their high magnetic moment and relatively long electronic relaxation time. In this study, the behavior of gadolinium ion as a contrast agent was investigated by two complementary methods, relaxometry and secondary ion mass spectrometry. The study examined the distribution of blood flow within the microvascular network in

Indexed as

Magnetic Resonance ImagingAnimalsContrast MediaGadoliniumHeartHeart FailureHumansMicrocirculationMyocardial ContractionRatsSpectrometry, Mass, Secondary IonWaterContrast MediaGadoliniumWatergadoliniumNMRD profilestissue microimagingToF-SIMS

Identifiers

PMID30884846
PMCPMC6471734
OpenAlexW2922297310

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.