Evidence map›Paper›PMID 30884827›Full record

ArticleCancers2019

Challenges Facing Radiation Oncologists in The Management of Older Cancer Patients: Consensus of The International Geriatric Radiotherapy Group.

Tiberiu Popescu, Ulf Karlsson, Vincent Vinh-Hung, Lurdes Trigo, Juliette Thariat, Te Vuong, Brigitta G Baumert, Micaela Motta, Alice Zamagni, Marta Bonet and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Pooled it
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  18. Practical brachytherapy solutions to an age-old quandary.Technical innovations & patient support in radiation oncology · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 10 countries.

Tiberiu PopescuDepartment of Radiation Oncology, Prof. Dr. Ion Chricuta Oncology Institute, Cluj-Napoca 400015, Romania. tiberiu_popescu14@yahoo.com.
Ulf KarlssonDepartment of Radiation Oncology, International Geriatric Radiotherapy Group, Washington, DC 20001, USA. karlssonulf30@gmail.com.
Vincent Vinh-HungDepartment of Radiation Oncology, University Hospital of Martinique, Martinique 97200, France. anhxang@gmail.com.ORCID 0000-0002-6403-6120
Lurdes TrigoDepartment of Radiation Oncology, Instituto Portugues de Oncologia Francisco Martins Porto E.P.E, Porto 4200-072, Portugal. lurdes.trigo@ipoporto.min-saude.pt.
Juliette ThariatDepartment of Radiation Oncology, Baclesse Cancer Center, Caen 14000, France. jthariat@gmail.com.
Te VuongDepartment of Radiation Oncology, McGill University, Montreal H3T 1E2, Canada. te.vuong@mcgill.ca.
Brigitta G BaumertDepartment of Radiation Oncology, University of Bonn, Bonn 43217, Germany. brigitta.baumert@gmail.com.
Micaela MottaDepartment of Radiation Oncology, Humanitas Gavazzeni Bergamo, Bergamo 24125, Italy. motta.micaela@libero.it.
Alice ZamagniRadiation Oncology Center, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna 40138, Italy. alice.zamagni4@unibo.it.
Marta BonetDepartment of Radiation Oncology, Arnau de Vilanova University Hospital, Lleida 25198, Spain. bonet.marta@gmail.com.
Arthur Sun MyintDepartment of Radiation Oncology, Clattterbridge Cancer Center, Liverpool CH63 4JY, UK. sun.myint@nhs.net.
Pedro Carlos LaraDepartment of Radiation Oncology, Fernando Pessoa Canarias Las Palmas University, Las Palmas 35010, Spain. pedrocarlos.lara@ulpgc.es.
Nam P NguyenDepartment of Radiation Oncology, Howard University, Washington, DC 20060, USA. namphong.nguyen@yahoo.com.ORCID 0000-0001-5106-6665
Meritxell ArenasDepartment of Radiation Oncology, Sant Joan de Reus University, University Rovira i Virgili, Tarragona 43204, Spain. meritxell.arenas@gmail.com.
Centre François Baclesse · FRCentre Hospitalier Universitaire de Martinique · MQClatterbridge Cancer Centre NHS Foundation Trust · GBHospital Universitari Arnau de Vilanova · ESHospital Universitari Sant Joan de Reus · ESHoward University · USHumanitas Gavazzeni · ITInstitute of Oncology Prof. Dr. Ion Chiricuta · ROIPO Porto · PTIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITMcGill University · CAUniversidad Fernando Pessoa Canarias · ESUniversity of Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of older cancer patients remains difficult because of data paucity. Radiation oncologists need to identify potential issues which could affect treatment of those patients. A workshop was organized in Barcelona among international radiation oncologists with special interest in the management of older cancer patients on April 22, 2018. The following consensus was reached: 1. Older cancer patients often faced unconscious discriminating bias from cancer specialists and institutions because of their chronological age. 2. Advances in radiotherapy techniques have allowed patients with multiple co-morbidities precluding surgery or systemic therapy to achieve potential cure in early disease stages. 3. The lack of biomarkers for frailty remains an impediment to future research. 4. Access to healthcare insurance and daily transportation remains an issue in many countries; 5. Hypofractionation, brachytherapy, or stereotactic techniques may be ideally suited for older cancer patients to minimize transportation issues and to improve tolerance to radiotherapy. 6. Patients with locally advanced disease who are mentally and physically fit should receive combined therapy for potential cure. 7. The role of systemic therapy alone or combined with radiotherapy for frail patients needs to be defined in future clinical trials because of targeted agents or immunotherapy may be less toxic compared to conventional chemotherapy.

Indexed as

comorbiditydiscriminationfrailtyolderradiotherapy tolerance

Identifiers

PMID30884827
PMCPMC6468336
OpenAlexW2922258220

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.