Evidence map›Paper›PMID 30884081›Full record

ArticleEnvironmental microbiology2019

Riding the wave of genomics to investigate aquatic coliphage diversity and activity.

Slawomir Michniewski, Tamsin Redgwell, Aurelija Grigonyte, Branko Rihtman, Maria Aguilo-Ferretjans, Joseph Christie-Oleza, Eleanor Jameson, David J Scanlan, Andrew D Millard

Abstract read
In one paragraph

Article in Environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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  15. Isolation and Characterization ofPHAGE (New Rochelle, N.Y.) · 2021
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  20. The ecogenomics of dsDNA bacteriophages in feces of stabled and feral horses.Computational and structural biotechnology journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Slawomir MichniewskiSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Tamsin RedgwellSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Aurelija GrigonyteSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Branko RihtmanSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Maria Aguilo-FerretjansSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
Joseph Christie-OlezaSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.ORCID 0000-0002-0992-2226
Eleanor JamesonSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.
David J ScanlanSchool of Life Sciences, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL, UK.ORCID 0000-0003-3093-4245
Andrew D MillardDepartment of Genetics and Genome Biology, University of Leicester, University Road, Leicester LE1 7RH, UK.ORCID 0000-0002-3895-2854

Funding

Engineering and Physical Sciences Research CouncilMedical Research Council MR/L015080/1MRC CLIMB Infrastructure MR/L015080/1Natural Environment Research Council NE/N019881/1Natural Environment Research Council CENTA DTP
6 · The paper itself

Abstract

Bacteriophages infecting Escherichia coli (coliphages) have been used as a proxy for faecal matter and water quality from a variety of environments. However, the diversity of coliphages that is present in seawater remains largely unknown, with previous studies largely focusing on morphological diversity. Here, we isolated and characterized coliphages from three coastal locations in the United Kingdom and Poland. Comparative genomics and phylogenetic analysis of phage isolates facilitated the identification of putative new species within the genera Rb69virus and T5virus and a putative new genus within the subfamily Tunavirinae. Furthermore, genomic and proteomic analysis combined with host range analysis allowed the identification of a putative tail fibre that is likely responsible for the observed differences in host range of phages vB_Eco_mar003J3 and vB_Eco_mar004NP2.

Indexed as

ColiphagesEscherichia coliGenome, ViralGenomicsHost SpecificityMyoviridaePhylogenyPolandProteomicsSeawaterSiphoviridaeUnited Kingdom

Identifiers

PMID30884081
PMCPMC6563131

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.