Evidence map›Paper›PMID 30883980›Full record

ReviewJournal of internal medicine2019

Treatments and rehabilitation in the acute and chronic state of traumatic brain injury.

N Marklund, B-M Bellander, A K Godbolt, H Levin, P McCrory, E P Thelin

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

N MarklundDepartment of Clinical Sciences Lund, Neurosurgery, Lund University, Skane University Hospital, Lund, Sweden.
B-M BellanderDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
A K GodboltDepartment of Clinical Sciences, Karolinska Institutet, Danderyd Hospital, Stockholm, Sweden.
H LevinDepartment of Physical Medicine & Rehabilitation, Baylor College of Medicine, Houston, TX, USA.
P McCroryTBI Laboratory, Florey Institute of Neurosciences & Mental Health, Parkville, Vic, Australia.
E P ThelinDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-2338-4364

Funding

Imaging and Biomarkers in Adolescents Cleared for Return to Play After ConcussionR21NS086714 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI DASH, PRAMOD K, LEVIN, HARVEY · 2014 to 2015
$447k
NINDS NIH HHS R21 NS086714
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a major cause of acquired disability globally, and effective treatment methods are scarce. Lately, there has been increasing recognition of the devastating impact of TBI resulting from sports and other recreational activities, ranging from primarily sport-related concussions (SRC) but also more severe brain injuries requiring hospitalization. There are currently no established treatments for the underlying pathophysiology in TBI and while neuro-rehabilitation efforts are promising, there are currently is a lack of consensus regarding rehabilitation following TBI of any severity. In this narrative review, we highlight short- and long-term consequences of SRCs, and how the sideline management of these patients should be performed. We also cover the basic concepts of neuro-critical care management for more severely brain-injured patients with a focus on brain oedema and the necessity of improving intracranial conditions in terms of substrate delivery in order to facilitate recovery and improve outcome. Further, following the acute phase, promising new approaches to rehabilitation are covered for both patients with severe TBI and athletes suffering from SRC. These highlight the need for co-ordinated interdisciplinary rehabilitation, with a special focus on cognition, in order to promote recovery after TBI.

Indexed as

Brain InjuriesBrain Injuries, TraumaticBrain Injury, ChronicHumansInjury Severity ScorePatient Care Teamcognitionneuro-critical careneuro-rehabilitationsport-related concussiontraumatic brain injury

Identifiers

PMID30883980
PMCPMC6527474

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.