Evidence map›Paper›PMID 30883935›Full record

ArticleJournal of veterinary internal medicine2019

Sonography and sonoelastography in the detection of malignancy in superficial lymph nodes of dogs.

Alexandra F Belotta, Marcela C Gomes, Noeme S Rocha, Alessandra Melchert, Rogério Giuffrida, Jeana P Silva, Maria J Mamprim

Open access · goldAbstract readComparative Study
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Diagnostic Imaging Features of Mammary Gland Tumors in Dogs and Cats.Animals : an open access journal from MDPI · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alexandra F BelottaDepartment of Animal Reproduction and Veterinary Radiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.ORCID https://orcid.org/0000-0001-6233-5656
Marcela C GomesDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.
Noeme S RochaDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.
Alessandra MelchertDepartment of Veterinary Clinics, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.
Rogério GiuffridaDepartment of Preventive Veterinary Medicine, School of Veterinary Medicine, Oeste Paulista University, Presidente Prudente, Brazil.
Jeana P SilvaDepartment of Animal Reproduction and Veterinary Radiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.
Maria J MamprimDepartment of Animal Reproduction and Veterinary Radiology, School of Veterinary Medicine and Animal Science, Sao Paulo State University, Botucatu, Brazil.
University of Veterinary Medicine · HUUniversidade do Oeste Paulista · BR

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior CAPES PhD scholarship to Alexandra F.BelottaFundação de Amparo à Pesquisa do Estado de São Paulo FAPESP, process 2012/02484-2
6 · The paper itself

Abstract

backgroundThe clinical applicability of sonography and sonoelastography (SOE) in the detection of lymph node malignancy in dogs has not been established.

objectivesTo compare sonographic and sonoelastographic findings between malignant and benign superficial lymph nodes and to evaluate the diagnostic performance of those methods. ANIMALS: One-hundred sixteen lymph nodes of 54 dogs.

methodsA prospective observational study was used to investigate sonographic features and elasticity scores of malignant and benign superficial lymph nodes. Lymph nodes were categorized as malignant or benign according to cytology or histopathology. Quantitative variables were compared using Student's unpaired t test. Prevalence of categorical variables was compared using nonparametric Mann-Whitney U test. Diagnostic performance was calculated by receiver-operating characteristic analysis.

resultsForty-nine malignant and 67 benign lymph nodes were included. Malignant nodes had larger long axis (LA; P = .0002), short axis (SA; P < .0001) and short-to-long axis ratio (P < .0001) in comparison with benign nodes. Malignant nodes had a higher prevalence of mixed vascular distribution on Doppler color flow mapping (P < .005) and on power Doppler (P < .0001) and higher resistivity index (RI; P < .0001), pulsatility index (P < .0001), and elasticity score (P < .0001) in comparison with benign nodes. Short axis, elasticity score, and RI offered the best accuracies, 80.2%, 78.1%, and 77.7% (P < .05), respectively, for malignancy detection. CONCLUSIONS AND CLINICAL IMPORTANCE: Results support the use of Doppler sonography and SOE as auxiliary methods to brightness mode sonography to detect nodal malignancy.

Indexed as

AnimalsDiagnosis, DifferentialDog DiseasesDogsElasticity Imaging TechniquesLymphatic MetastasisLymph NodesLymphomaProspective StudiesUltrasonographycanineDopplerelastographylymphoid tissueultrasound

Identifiers

PMID30883935
PMCPMC6524127
OpenAlexW2923048843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.