ArticleMagnetic resonance in medicine2019
Enabling free-breathing background suppressed renal pCASL using fat imaging and retrospective motion correction.
Article in Magnetic resonance in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- Capability of multiparametric MRI to detect diabetic nephropathy in high-risk patients with type 2 diabetes: a prospective preliminary study.BMC medical imaging · 2026Article
- Longitudinal assessment of renal allograft function in donors and pediatric recipients by arterial spin labeling MRI perfusion quantification.Scientific reports · 2025Article
- An arterial spin labeling-based radiomics signature and machine learning for the prediction and detection of various stages of kidney damage due to diabetes.Frontiers in endocrinology · 2024Article
- Detection of impaired renal allograft function in paediatric and young adult patients using arterial spin labelling MRI (ASL-MRI).Scientific reports · 2022Article
- Multi-organ comparison of flow-based arterial spin labeling techniques: Spatially non-selective labeling for cerebral and renal perfusion imaging.Magnetic resonance in medicine · 2021Article
- Image registration in dynamic renal MRI-current status and prospects.Magma (New York, N.Y.) · 2020Review
- Consensus-based technical recommendations for clinical translation of renal ASL MRI.Magma (New York, N.Y.) · 2020Article
- Enabling free-breathing background suppressed renal pCASL using fat imaging and retrospective motion correction.Magnetic resonance in medicine · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFor free-breathing renal perfusion imaging using arterial spin labeling (ASL), retrospective image realignment has been found essential to reduce subtraction artifacts and, independently, background suppression has been demonstrated to reduce physiologic noise. However, negative results on ASL precision and accuracy have been reported for the combination of both. In this study, the effect of background suppression -level in combination with image registration on free-breathing renal ASL signal quality, with registration either on ASL-images themselves or guided by additionally acquired fat-images, was investigated. The results from free-breathing acquisitions were compared with the reference paced-breathing motion compensation strategy.
methodsPseudocontinuous ASL (pCASL) data with additional fat-images were acquired from 10 subjects at 1.5T with varying background suppression levels during free-breathing and paced-breathing. Images were registered using the ASL-images themselves (ASLReg) or using their corresponding fat-images (FatReg). Temporal signal-to-noise ratio (tSNR) served to evaluate precision and perfusion weighted signal (PWS) to assess accuracy.
resultsIn combination with image registration, background suppression significantly improved tSNR by 50% (P < .05). For heavy suppression, ASLReg and FatReg showed similar performance in terms of tSNR and PWS. Background suppression with two inversion pulses induced a small, nonsignificant (P > .05) PWS reduction, but increased PWS accuracy. When applying heavy background suppression, free-breathing acquisitions resulted in similar ASL-quality to paced-breathing acquisitions.
conclusionBackground suppression was found beneficial for free-breathing renal pCASL precision without compromising accuracy, despite motion challenges. In combination with ASLReg or FatReg, background suppression enabled clinically viable free-breathing renal pCASL.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.