Evidence map›Paper›PMID 30883640›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2020

How Does Smoking and Nicotine Dependence Change After Onset of Vaping? A Retrospective Analysis of Dual Users.

Úrsula Martínez, Víctor Martínez-Loredo, Vani N Simmons, Lauren R Meltzer, David J Drobes, Karen O Brandon, Amanda M Palmer, Thomas Eissenberg, Christopher R Bullen, Paul T Harrell and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Changes in Nicotine Dependence Among Smokers Using Electronic Cigarettes to Reduce Cigarette Smoking in a Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
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  17. Examining Electronic Nicotine Delivery System (ENDS) Cue Reactivity Using a Remote Platform: Cigarette and ENDS Desire in Dual Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
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  18. Trends and Sociodemographic Differences in Tobacco/Nicotine Transitions Among U.S. Adolescents and Young Adults Using e-cigarettes, 2014-2023.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2025
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Úrsula MartínezDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
Víctor Martínez-LoredoClinical Unit of Addictive Behaviors, Department of Psychology, University of Oviedo, Spain.
Vani N SimmonsDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
Lauren R MeltzerDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
David J DrobesDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
Karen O BrandonDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
Amanda M PalmerDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.
Thomas EissenbergCenter for the Study of Tobacco Products, Department of Psychology, Virginia Commonwealth University, Richmond, VA.
Christopher R BullenSchool of Population Health, Faculty of Medical and Health Science, University of Auckland, New Zealand.
Paul T HarrellDepartment of Pediatrics, Eastern Virginia Medical School, Norfolk, VA.
Thomas H BrandonDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL.

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-CigarettesR01DA037961 · NIDA · H. LEE MOFFITT CANCER CTR & RES INST · PI BRANDON, THOMAS H · 2015 to 2019
$3.7M
The Impact of Design Characteristics on the Modification Potential of Electronic Nicotine Delivery SystemsR01DA047397 · NIDA · GEORGIA STATE UNIVERSITY · PI ASHLEY, DAVID LIDDELL, POPOVA, LYUDMILA · 2018 to 2020
$1.6M
Measure Development for Prediction of E-cigarette InitiationR03CA195124 · NCI · EASTERN VIRGINIA MEDICAL SCHOOL · PI HARRELL, PAUL TRUMAN · 2015 to 2016
$166k
NCI NIH HHS P30 CA076292NCI NIH HHS R03 CA195124NIDA NIH HHS R01 DA037961
6 · The paper itself

Abstract

introductionAlthough some smokers switch to exclusive use of electronic cigarettes (e-cigarettes), others become dual users of combustible cigarettes and e-cigarettes. Little is known about how the onset of vaping affects the use of and dependence on combustible cigarettes or total nicotine use and dependence, which may influence health-related and cessation outcomes. Using self-report data of current combustible and e-cigarette use and retrospective recall of pre-vaping smoking in a sample of dual users, the aims of this study were (1) to compare pre- and post-vaping number of cigarettes per day and combustible cigarette dependence; (2) to compare pre- and post-vaping total nicotine use frequency (number of vaping sessions and cigarettes smoked per day), and total nicotine dependence; and (3) to examine predictors of nicotine dependence.

methodsWe used baseline data from a smoking cessation trial with 2896 dual users. Nicotine use frequency and the Heaviness of Smoking Index were used as measures of nicotine use and dependence, respectively.

resultsParticipants decreased cigarettes/day from pre- (M = 19.24, SD = 9.01) to post-vaping (M = 11.15, SD = 8.02, p < .0001) and combustible cigarette dependence declined from pre- (M = 3.55, SD = 1.51) to post-vaping (M = 2.11, SD = 1.60, p < .0001). Total daily nicotine use frequency increased after initiating vaping (M = 19.25, SD = 9.01 vs. M = 29.46, SD = 8.61; p < .0001), as did total nicotine dependence (M = 3.55, SD = 1.51 vs. M = 4.68, SD = 1.38; p < .0001). Hierarchical regression analyses indicated that variables associated with greater overall nicotine dependence included: younger age, lower education, more years smoking, higher pre-vaping nicotine dependence, using e-cigarettes more days per month, more puffs per vaping session, higher e-liquid nicotine concentration, and longer vaping history.

conclusionsDual use leads to a reduction in the number of combustible cigarettes, but total nicotine use and dependence increases. IMPLICATIONS: In dual users, a reduction in smoking following onset of vaping may offer some harm reduction via reduction in cigarette intake. However, the increase in total nicotine use and dependence could affect the ability to quit either or both products.

Indexed as

AdultElectronic Nicotine Delivery SystemsFemaleHarm ReductionHumansMaleRetrospective StudiesSelf ReportSmokersSmoking CessationTobacco SmokingTobacco Use DisorderUnited StatesVaping

Identifiers

PMID30883640
PMCPMC7171272

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.