ArticleJournal of medicinal chemistry2019
Dopamine D
Open access · greenAbstract read
In one paragraph
Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 31 citations in OpenAlex.
- Investigating substituted phenylacetamide ligands in the DBioorganic & medicinal chemistry letters · 2026Article
- Novel dopamine 4 receptor ligands differentially ameliorate ADHD-like behaviors in spontaneously hypertensive rats.Psychopharmacology · 2026Article
- Bioisosteric Replacement of Amides with 1,2,3-Triazoles Improves Dopamine D4 Receptor Ligand Pharmacokinetics.ACS pharmacology & translational science · 2026Article
- Apomorphine differentially engages the cAMP and β-arrestin signaling pathways relative to dopamine at human dopamine receptors.Journal of neural transmission (Vienna, Austria : 1996) · 2025Article
- Contrastive explanations for machine learning predictions in chemistry.Journal of cheminformatics · 2025Article
- Exploring the impact of deleterious missense nonsynonymous single nucleotide polymorphisms in the DRD4 gene using computational approaches.Scientific reports · 2025Article
- Development of Novel Tools for Dissection of Central Versus Peripheral Dopamine D2-Like Receptor Signaling in Dysglycemia.Diabetes · 2024Article
- Pharmacology and Therapeutic Potential of Benzothiazole Analogues for Cocaine Use Disorder.Journal of medicinal chemistry · 2023Article
- Dopamine-induced arrestin recruitment and desensitization of the dopamine D4 receptor is regulated by G protein-coupled receptor kinase-2.Frontiers in pharmacology · 2023Article
- Highly Potent and Selective Dopamine DJournal of medicinal chemistry · 2022Article
- Reflections of six neuroscientists: The influences of training at minority serving institutions.Journal of neuroscience research · 2022Article
- Identification of Novel Dopamine DMolecules (Basel, Switzerland) · 2022Article
- Discovery and characterization of benzyloxy piperidine based dopamine 4 receptor antagonists.Bioorganic & medicinal chemistry letters · 2022Article
- Chiral Cyclic Aliphatic Linkers as Building Blocks for Selective Dopamine DJournal of medicinal chemistry · 2021Article
- Novel Dual-Target μ-Opioid Receptor and Dopamine DJournal of medicinal chemistry · 2021Article
- Exception That Proves the Rule: Investigation of Privileged Stereochemistry in Designing Dopamine DACS medicinal chemistry letters · 2020Article
- A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity.Science signaling · 2020Article
- The Significance of Chirality in Drug Design and Synthesis of Bitopic Ligands as DJournal of medicinal chemistry · 2019Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 4 institutions in 1 country.
Thomas M KeckDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.ORCID 0000-0003-1845-9373
R Benjamin FreeMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program , National Institutes of Health , Bethesda , Maryland 20892 , United States.
Marilyn M DayMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program , National Institutes of Health , Bethesda , Maryland 20892 , United States.
Sonvia L BrownDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy , High Point University , One University Parkway , High Point , North Carolina 27268 , United States.
Michele S MaddalunaDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy , High Point University , One University Parkway , High Point , North Carolina 27268 , United States.
Griffin FountainDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.
Charles CooperDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.
Brooke FallonDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.
Matthew HolmesDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.
Christopher T StangMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program , National Institutes of Health , Bethesda , Maryland 20892 , United States.
Russell BurkhardtMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program , National Institutes of Health , 333 Cassell Drive , Baltimore , Maryland 21224 , United States.
Alessandro BonifaziMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program , National Institutes of Health , 333 Cassell Drive , Baltimore , Maryland 21224 , United States.
Michael P EllenbergerMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program , National Institutes of Health , 333 Cassell Drive , Baltimore , Maryland 21224 , United States.
Amy H NewmanMedicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse-Intramural Research Program , National Institutes of Health , 333 Cassell Drive , Baltimore , Maryland 21224 , United States.ORCID 0000-0001-9065-4072
David R SibleyMolecular Neuropharmacology Section, National Institute of Neurological Disorders and Stroke-Intramural Research Program , National Institutes of Health , Bethesda , Maryland 20892 , United States.
Chun WuDepartment of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, College of Science and Mathematics , Rowan University , 201 Mullica Hill Road , Glassboro , New Jersey 08028 , United States.
Comfort A BoatengDepartment of Basic Pharmaceutical Sciences, Fred Wilson School of Pharmacy , High Point University , One University Parkway , High Point , North Carolina 27268 , United States.ORCID 0000-0003-1907-431X
National Institutes of Health · USRowan University · USHigh Point University · USCooper Medical School of Rowan University · US
Funding
Molecular And Pharmacological Studies Of Dopamine ReceptorsZIANS002263 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SIBLEY, DAVID · 2009 to 2025
$37.4MDopamine D2-like Functionally Selective AgonistsZIADA000609 · NIDA · NATIONAL INSTITUTE ON DRUG ABUSE · PI NEWMAN, AMY HAUCK · 2016 to 2020
$2.8MIntramural NIH HHS ZIA DA000609
Abstract
The dopamine D
Indexed as
AnimalsCHO CellsCricetulusDopamine AgonistsHumansLigandsReceptors, Dopamine D4Structure-Activity RelationshipDopamine AgonistsLigandsReceptors, Dopamine D4
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.