ArticleEnvironmental microbiology2019
The regulatory network of Vibrio parahaemolyticus type VI secretion system 1.
Article in Environmental microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Neisseria subflava Type 6 Secretion System competition with bacterial and fungal species.Applied microbiology and biotechnology · 2026Article
- Functional divergence and regulatory network of the type VI secretion system inJournal of bacteriology · 2026Review
- The multifunctional type VI secretion system ofApplied and environmental microbiology · 2025Review
- Bile acids activate the antibacterial T6SS1 in the gut pathogenMicrobiology spectrum · 2024Article
- Article
- Validation of the Thermo Scientific™ SureTect™ Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus PCR Assay for the Detection of Vibrio cholerae, Vibrio parahaemolyticus, and Vibrio vulnificus in Seafood Matrixes: AOAC Performance Tested MethodsSM 022301.Journal of AOAC International · 2023Article
- Regulation of type VI secretion systems at the transcriptional, posttranscriptional and posttranslational level.Microbiology (Reading, England) · 2023Review
- Sporadic type VI secretion in seventh pandemicMicrobiology (Reading, England) · 2023Article
- A Novel Transcription Factor VPA0041 Was Identified to Regulate the Swarming Motility inPathogens (Basel, Switzerland) · 2022Article
- Characterization of the RpoN regulon reveals the regulation of motility, T6SS2 and metabolism inFrontiers in microbiology · 2022Article
- Genetic Basis of High-Pressure Tolerance of aFrontiers in microbiology · 2022Article
- A Rapid Fluorescence-Based Screen to Identify Regulators and Components of Interbacterial Competition Mechanisms in Bacteria.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Rapid detection ofRSC advances · 2021Article
- Engineering a customizable antibacterial T6SS-based platform in Vibrio natriegens.EMBO reports · 2021Article
- The substrate-dependent regulatory effects of the AfeI/R system in Acidithiobacillus ferrooxidans reveals the novel regulation strategy of quorum sensing in acidophiles.Environmental microbiology · 2021Article
- Role of the Type VI Secretion System in the Pathogenicity ofFrontiers in microbiology · 2021Article
- Adaptations ofFrontiers in microbiology · 2021Review
- A comparative genomics methodology reveals a widespread family of membrane-disrupting T6SS effectors.Nature communications · 2020Article
- Comparative Proteomics and Secretomics Revealed Virulence and Antibiotic Resistance-Associated Factors inFrontiers in microbiology · 2020Article
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Abstract
Type VI secretion systems (T6SSs) are widespread, tightly regulated, protein delivery apparatuses used by Gram-negative bacteria to outcompete their neighbours. The pathogen, Vibrio parahaemolyticus, encodes two T6SSs. These T6SSs are differentially regulated by external conditions. T6SS1, an antibacterial system predominantly found in pathogenic isolates, requires warm marine-like conditions and surface sensing for activation. The regulatory network that governs this activation is not well understood. In this work, we devised a screening methodology that allows us to easily monitor the outcome of bacterial competitions and thus to identify mutants that are defective in T6SS1-mediated bacterial killing. The methodology, termed Bacterial Competition Fluorescence (BaCoF), relies on detection of a fluorescent signal as an indicator of the survival and growth of a T6SS-sensitive, GFP-expressing prey that has been co-cultured with mutants derived from a T6SS
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