Evidence map›Paper›PMID 30882956›Full record

ReviewJournal of neuroendocrinology2019

Mechanisms for the metabolic success of bariatric surgery.

Darleen A Sandoval

Abstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Roux-en-Y gastric bypass alters microbial circadian rhythms with links to metabolic improvement.American journal of physiology. Gastrointestinal and liver physiology · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Long-term cancer outcomes after bariatric surgery.Obesity (Silver Spring, Md.) · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Bile-ology: from bench to bedside.Journal of Zhejiang University. Science. B · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Darleen A SandovalDepartment of Surgery, University of Michigan, Ann Arbor, Michigan.ORCID 0000-0003-3669-3278

Funding

A novel paracrine role for GLP-1 in the isletR01DK107282 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANDOVAL, DARLEEN A. · 2017 to 2020
$1.6M
NIDDK NIH HHS R01 DK107282
6 · The paper itself

Abstract

To date, bariatric surgery remains the most effective strategy for the treatment of obesity and its comorbidities. However, given the enormity of the obesity epidemic, and sometimes variable results, it is not a feasible strategy for the treatment of all obese patients. A simple PubMed search for 'bariatric surgery' reveals over 28 000 papers that have been published since the 1940s when the first bariatric surgeries were performed. However, there is still an incomplete understanding of the mechanisms for the weight loss and metabolic success of surgery. An understanding of the mechanisms is important because it may lead to greater understanding of the pathophysiology of obesity and thus surgery-alternative strategies for the treatment of all obese patients. In this review, the potential mechanisms that underlie the success of surgery are discussed, with a focus on the potential endocrine, neural and other circulatory factors (eg, bile acids) that have been proposed to play a role.

Indexed as

Bariatric SurgeryAnimalsFeeding BehaviorGastrointestinal MicrobiomeGastrointestinal TractHumansObesityWeight Lossbariatric surgerybile acidsmetabolism

Identifiers

PMID30882956
PMCPMC9205614

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.