Evidence map›Paper›PMID 30882924›Full record

ArticlePacing and clinical electrophysiology : PACE2019

Comparing phase and electrographic flow mapping for persistent atrial fibrillation.

M Swerdlow, M Tamboli, M I Alhusseini, N Moosvi, A J Rogers, G Leef, P J Wang, A Rillig, J Brachmann, W H Sauer and 3 more

Open access · greenAbstract readComparative StudyMulticenter Study
In one paragraph

Article in Pacing and clinical electrophysiology : PACE, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Navigating the Ebb and Flow of Atrial Fibrillation.JACC. Clinical electrophysiology · 2024
    Article
  4. Electrographic flow mapping of persistent atrial fibrillation: intra- and inter-procedure reproducibility in the absence of 'ground truth'.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Future Directions for Mapping Atrial Fibrillation.Arrhythmia & electrophysiology review · 2022
    Review
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Another method that shows organization in persistent AF? That's a RAAP.Journal of cardiovascular electrophysiology · 2019
    Article
  17. Review
  18. Article
  19. Editorial: High density mapping of atrial fibrillation sources.Journal of cardiovascular electrophysiology · 2019
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

M SwerdlowCardiovascular Medicine, Stanford University, Stanford, California.
M TamboliCardiovascular Medicine, Stanford University, Stanford, California.
M I AlhusseiniCardiovascular Medicine, Stanford University, Stanford, California.
N MoosviCardiovascular Medicine, Stanford University, Stanford, California.
A J RogersCardiovascular Medicine, Stanford University, Stanford, California.
G LeefCardiovascular Medicine, Stanford University, Stanford, California.
P J WangCardiovascular Medicine, Stanford University, Stanford, California.
A RilligCardiology, Asklepios Klinik St. Georg, Hamburg, Germany.
J BrachmannCardiology, II Medizinische Klinik Klinikum Coburg, Coburg, Germany.
W H SauerCardiology, University of Colorado at Denver and Health Sciences Center, Denver, Colorado.
P RuppersbergAblacon, Wheat Ridge, Colorado.
S M NarayanCardiovascular Medicine, Stanford University, Stanford, California.
T BaykanerCardiovascular Medicine, Stanford University, Stanford, California.ORCID 0000-0002-0476-2972
Cardiovascular Institute of the South · USAsklepios Klinik St. Georg · DEKlinikum Coburg · DESouthern Nursing Research Society · USUniversity of Colorado Hospital · US

Funding

The Dynamics of Human Atrial FibrillationR01HL083359 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sanjiv M Narayan · 2008 to 2026
$7.9M
The Maintenance of Human Atrial FibrillationK24HL103800 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NARAYAN, SANJIV M · 2010 to 2019
$1.9M
Deep Neural Networks To Treat Atrial FibrillationK23HL145017 · NHLBI · STANFORD UNIVERSITY · PI BAYKANER, TINA · 2019 to 2023
$968k
Novel Atrial Fibrillation Phenotypes Defined by Functional-Anatomical, Machine-Learned ClassificationsF32HL144101 · NHLBI · STANFORD UNIVERSITY · PI ROGERS, ALBERT JOSEPH · 2018 to 2019
$130k
NHLBI NIH HHS F32 HL144101NHLBI NIH HHS K23 HL145017NHLBI NIH HHS K24 HL103800NHLBI NIH HHS R01 HL083359
6 · The paper itself

Abstract

backgroundAn increasing number of methods are being used to map atrial fibrillation (AF), yet the sensitivity of identifying potential localized AF sources of these novel methods are unclear. Here, we report a comparison of two approaches to map AF based upon (1) electrographic flow mapping and (2) phase mapping in a multicenter registry of patients in whom ablation terminated persistent AF.

methodsFifty-three consecutive patients with persistent AF in whom ablation terminated AF in an international multicenter registry were enrolled. Electrographic flow mapping (EGF) and phase mapping were applied to the multipolar simultaneous electrograms recorded from a 64-pole basket catheter in the chamber (left vs right atrium) where AF termination occurred. We analyzed if the mapping methods were able to detect localized sources at the AF termination site. We also analyzed global results of mapping AF for each method, patterns of activation of localized sources.

resultsPatients were 64.3 ± 9.4 years old and 69.8% were male. EGF and phase mapping identified localized sources at AF termination sites in 81% and 83% of the patients, respectively. Methods were complementary and in only n = 2 (3.7%) neither method identified a source. Globally, EGF identified more localized sources than phase mapping (5.3 ± 2.8 vs 1.8 ± 0.5, P < 0.001), with a higher prevalence of focal (compared to rotational) activation pattern (49% vs 2%, P < 0.01).

conclusionsEGF is a novel vectorial-based AF mapping method, which can detect sites of AF termination, agreeing with, and complementary to, an alternative AF mapping method using phase analysis.

Indexed as

ElectrocardiographyEpicardial MappingAtrial FibrillationCatheter AblationFemaleHumansMaleMiddle AgedRegistriesatrial fibrillationelectrographic flowelectrophysiologymappingphase

Identifiers

PMID30882924
PMCPMC6476687
OpenAlexW2922091351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.