Evidence map›Paper›PMID 30882696›Full record

ArticleMedicine2019

Immunocompetent patient with a brain abscess caused by Nocardia beijingensis in Latin America: A case report.

David M Solano-Varela, Edgar M Barrios-Vidales, David F Plaza, William M Riveros, Julián Guzmán, Claudia E Chica, Manuel A Patarroyo

Open access · goldAbstract readCase Reports
In one paragraph

Article in Medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Clinical Characteristics and Treatment Outcome of Central Nervous System Nocardiosis: A Systematic Review of Reported Cases.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2022
    Pooled it
  2. Article
  3. PersistentInfectious medicine · 2023
    Article
  4. Cerebral Abscess Infected byInfection and drug resistance · 2023
    Article
  5. Article
  6. Open forum infectious diseases · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. [Abscesos cerebrales por Nocardia spp. en una paciente inmunocompetente].Biomedica : revista del Instituto Nacional de Salud · 2020
    Article
  12. Multiple brain abscesses due to Nocardia spp. in an immunocompetent patientBiomedica : revista del Instituto Nacional de Salud · 2020
    Article
  13. DisseminatedEuropean journal of case reports in internal medicine · 2020
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

David M Solano-VarelaHospital Universitario Mayor Méderi, Universidad del Rosario.
Edgar M Barrios-VidalesHospital Universitario Mayor Méderi, Universidad del Rosario.
David F PlazaMolecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC).
William M RiverosHospital Universitario Mayor Méderi, Universidad del Rosario.
Julián GuzmánHospital Universitario Mayor Méderi, Universidad del Rosario.
Claudia E ChicaClinical lab, Compensar.
Manuel A PatarroyoMolecular Biology and Immunology Department, Fundación Instituto de Inmunología de Colombia (FIDIC).
Universidad del Rosario · COFundación Instituto de Inmunología de Colombia · CO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

rationaleNocardia species are not commonly referred as primary infectious entities but rather as opportunistic pathogens. Infectious cases of Nocardia spp. in immunocompetent individuals are rare. PATIENT CONCERNS: An immunocompetent 58-year-old patient presented with recurrent headaches. DIAGNOSIS: A brain abscess was found and surgically drained. Matrix-assisted laser desorption ionization-time-of-flight mass spectrometry and heat shock protein 65/16S-23S rRNA gene intergenic spacer genotyping from the sample revealed the etiological agent as Nocardia beijingensis.

interventionsMeropenem/amikacin/Trimethoprim-sulfamethoxazole were administered. OUTCOMES: The infection persisted leading to the patient's death. LESSONS: Here we present the first case of N. beijingensis infection of the central nervous system in an immunocompetent patient from Latin America. Further inquiry is needed to establish whether this species is more virulent than other Nocardia isolates.

Indexed as

Anti-Bacterial AgentsBrain AbscessHumansLatin AmericaMaleMeropenemMiddle AgedNocardiaNocardia InfectionsTomography, X-Ray ComputedTrimethoprim, Sulfamethoxazole Drug CombinationAnti-Bacterial AgentsMeropenemTrimethoprim, Sulfamethoxazole Drug Combination

Identifiers

PMID30882696
PMCPMC6426588
OpenAlexW2921779250

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.